AI Article Synopsis

  • Oral propranolol is a standard treatment for infantile hemangioma, but its safety in PHACE syndrome is uncertain due to stroke risks.
  • A four-month-old girl with PHACE syndrome and a significant facial hemangioma was effectively treated with propranolol.
  • The treatment was successful without any reported negative side effects.

Article Abstract

Oral propranolol is commonly used as a first-line treatment for infantile hemangioma. However, its use in PHACE (posterior fossa anomalies, hemangioma, arterial anomalies, cardiac anomalies, and eye anomalies) syndrome raises concerns that it might exacerbate the patient's risk of stroke. Here, we report the case of a four-month-old premature girl with PHACE syndrome, who presented with a large hemangioma involving the left side of her face, following the V1+V2+V3 distribution, including the upper lip, left ear, and left eye. This condition was successfully treated with propranolol, and no adverse side effects were reported.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457131PMC
http://dx.doi.org/10.7759/cureus.44036DOI Listing

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