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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450450 | PMC |
| http://dx.doi.org/10.7196/AJTCCM.2023.v29i2.803 | DOI Listing |
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Cells are subjected to dynamic mechanical environments which impart forces and induce cellular responses. In age-related conditions like pulmonary fibrosis, there is both an increase in tissue stiffness and an accumulation of senescent cells. While senescent cells produce a senescence-associated secretory phenotype (SASP), the impact of physical stimuli on both cellular senescence and the SASP is not well understood.
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