AI Article Synopsis

  • Calcium channel blockers, particularly amlodipine, can lead to serious cardiovascular toxicity with varying clinical outcomes.
  • A case study of a 43-year-old transgender woman illustrates complications like hypotension and tachycardia resulting from amlodipine overdose.
  • It's crucial to recognize amlodipine as a potential but often overlooked cause of drug overdose due to its severe effects.

Article Abstract

Calcium channel blockers are a major cause of cardiovascular toxicity. The clinical spectrum of these patients is very variable and there is no consensus on the dose required for toxicity. We present a case of a 43-year-old transgender woman who presented with hypotension and tachycardia owing to drug overdose that was later confirmed to be amlodipine. Given the catastrophic cascade of events involved with such toxicities, it is important to highlight amlodipine as one of the causes of drug overdose that can be overlooked.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457432PMC
http://dx.doi.org/10.7759/cureus.42511DOI Listing

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