AI Article Synopsis
- Kimura Disease is an eosinophilic granulomatous condition primarily affecting young males, characterized by deep tissue swelling and enlarged salivary glands.
- Diagnosis relies on histopathological analysis, elevated serum IgE levels, and hypereosinophilia, with Magnetic Resonance Imaging as the preferred imaging method.
- Treatment options include surgery, steroid therapy, and sometimes chemotherapy, but managing the disease is challenging due to the likelihood of relapse and recurrence.
Article Abstract
Unlabelled: Kimura Disease, an eosinophilic hyperplastic granulomatous disease of idiopathic origin is most commonly seen in young males. It mostly presents with deep subcutaneous tissue swelling along with enlargement of salivary glands and regional lymphadenopathy. Diagnosis is mainly based on histopathological findings and raised serum IgE and hypereosinophilia. The radiological investigation of choice is Magnetic Resonance Imaging. Management strategy includes surgery and steroid therapy. Chemotherapeutic agents are also frequently used by some centres. Relapse and recurrence stands to be a common problem with management of this disease process.
Supplementary Information: The online version contains supplementary material available at 10.1007/s12070-023-03817-y.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447794 | PMC |
| http://dx.doi.org/10.1007/s12070-023-03817-y | DOI Listing |
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