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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448617PMC
http://dx.doi.org/10.1002/mdc3.13768DOI Listing

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Article Synopsis
  • Anti-IgLON5 disease is characterized by various neurological symptoms, notably dysautonomia, which often does not respond to typical immunotherapy.
  • A patient with this condition exhibited multiple autonomic failures, including severe vocal cord palsy, cognitive issues, and motor and gastrointestinal dysfunctions.
  • However, after receiving combined immunotherapy, the patient's symptoms—including the vocal cord palsy—showed significant improvement, indicating potential benefits of this treatment approach for dysautonomia in anti-IgLON5 disease.
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Unusual tremor syndromes: know in order to recognise.

J Neurol Neurosurg Psychiatry

November 2016

Division of Neurology, Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

Tremor is a common neurological condition in clinical practice; yet, few syndromes are widely recognised and discussed in the literature. As a result, there is an overdiagnosis of well-known causes, such as essential tremor. Many important unusual syndromes should be considered in the differential diagnosis of patients with tremor.

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The clinical manifestations of 24 cases and the autopsy findings of 6 cases of extremity myorhythmia are presented. Extremity myorhythmia is that form of myorhythmia in which rhythmic alternating movements predominantly involve the limbs. The main difference between the tremor of extremity myorhythmia and the tremor of parkinsonism is the slower tremor rate, 2 to 3 cycles/s in myorhythmia and 4 to 6 cycles/s in parkinsonism.

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