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Similar Publications
A human brain network linked to restoration of consciousness after deep brain stimulation.
medRxiv
October 2024
Department of Neurosurgery, Mass General Brigham, Harvard Medical School, Boston, MA, USA.
Article Synopsis
- Disorders of consciousness (DoC) refer to conditions where a person has reduced awareness or ability to respond, and deep brain stimulation (DBS) is being explored as a treatment, with varying effectiveness based on patient specifics and stimulation methods.
- In a study of 40 DoC patients receiving DBS, improved consciousness was linked to better gray matter preservation, particularly in the striatum, and effective stimulation targeted specific brain areas, particularly the thalamic centromedian-parafascicular complex.
- The research highlights the need for precise electrode placement and suggests a connection between successful DBS treatment for DoC and mechanisms involved in other conditions that impair consciousness, such as absence seizures and brain lesions
Deep brain stimulation for Tourette's syndrome.
Neurosurg Rev
October 2024
Department of Neurosurgery, New York University Grossman School of Medicine, New York City, NYC, USA.
Article Synopsis
- Tourette's syndrome is a neuropsychiatric disorder marked by severe motor and vocal tics, often accompanied by other mental health issues, and can require more invasive treatments like Deep Brain Stimulation (DBS) for severe cases that don't respond to standard therapies.
- DBS targets specific brain regions, such as the globus pallidus internus and the thalamus, and has shown effectiveness in reducing tic severity and improving patients' quality of life, though results can vary based on factors like electrode placement.
- Ethical concerns surrounding DBS include surgical risks, the importance of informed consent, and potential impacts on cognitive and emotional development, highlighting the need for ongoing research and ethical discussions as DBS technology evolves.
CM-Pf deep brain stimulation in polyneuromodulation for epilepsy.
Epileptic Disord
October 2024
Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA.
Article Synopsis
- Neuromodulation is a promising option for drug-resistant epilepsy, showcasing case studies involving patients with multiple deep brain stimulators and their responses.
- A thorough review of literature indicates that combining vagus nerve stimulation, responsive neurostimulation, and deep brain stimulation is increasingly reported for treating these patients.
- A notable case is presented where a 28-year-old male with drug-resistant focal epilepsy achieved a 75% seizure reduction through the centromedian-parafascicular deep brain stimulation after inadequate results from previous treatments, emphasizing the safety and effectiveness of dual-device therapies.
Letter of response to "concerns about efficacy of deep brain stimulation (DBS) in centromedian-parafascicular thalamic complex for rapid onset dystonia-parkinsonism (DYT12-ATP1A3)".
Brain Stimul
April 2024
Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. Electronic address:
Concerns about efficacy of deep brain stimulation (DBS) in centromedian-parafascicular thalamic complex for rapid onset dystonia-parkinsonism (DYT12-ATP1A3).
Brain Stimul
April 2024
Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
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