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Real-world use of the CarestartTM glucose-6-phosphate dehydrogenase rapid diagnostic test to determine G6PD deficiency in Nigerian neonates.
J Trop Pediatr
October 2024
Department of Pediatrics, University of Minnesota, Minneapolis, MN, 55414, United States.
G6PD deficiency (G6PDd) is the most common X-linked genetic disease worldwide and the most common cause of severe neonatal hyperbilirubinemia (NH) in Nigeria. Screening for G6PDd has been recommended for over thirty years but is still not routinely done in Nigeria. We sought to investigate a low-cost rapid diagnostic test to determine G6PDd in Nigerian neonates.
View Article and Find Full Text PDFCOVID-19 pandemic effects on neonatal inpatient admissions and mortality: interrupted time series analysis of facilities implementing NEST360 in Kenya, Malawi, Nigeria, and Tanzania.
BMC Pediatr
July 2024
Maternal, Adolescent, Reproductive & Child Health (MARCH) Centre, London School of Hygiene & Tropical Medicine, London, UK.
Background: The emergence of COVID-19 precipitated containment policies (e.g., lockdowns, school closures, etc.
View Article and Find Full Text PDFTime to full enteral feeds in hospitalised preterm and very low birth weight infants in Nigeria and Kenya.
PLoS One
March 2024
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Article Synopsis
- Preterm and very low birthweight (VLBW) infants face high health risks in their early days, with full enteral feeding being crucial for their care, especially in sub-Saharan Africa where data on feeding practices is limited.
- This study analyzed demographic and clinical data from 484 preterm and VLBW infants across 7 neonatal units in Nigeria and Kenya to assess factors affecting the time to achieve full enteral feeds.
- Results indicated a significant percentage of mortality before feeding, revealing that earlier first feeds and gestational age greatly influenced the time to reach full enteral feeds, suggesting that implementing standardized feeding guidelines could improve outcomes in these infants.
Protecting small and sick newborn care in the COVID-19 pandemic: multi-stakeholder qualitative data from four African countries with NEST360.
BMC Pediatr
November 2023
Maternal, Adolescent, Reproductive & Child Health (MARCH) Centre, London School of Hygiene & Tropical Medicine, London, UK.
Background: Health system shocks are increasing. The COVID-19 pandemic resulted in global disruptions to health systems, including maternal and newborn healthcare seeking and provision. Yet evidence on mitigation strategies to protect newborn service delivery is limited.
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