Zn is involved in various physiological and pathological processes in living systems. Monitoring the dynamic spatiotemporal changes of Zn levels in organelles, cells, and in vivo is of great importance for the investigation of the physiological and pathological functions of Zn. However, this task is quite challenging since Zn in living systems is present at low concentrations and undergoes rapid dynamic changes. In this review, we summarize the design and application of fluorescent probes for Zn imaging in organelles, cells, and live organisms reported over the past two years. We aim to provide inspiration for the design of novel Zn probes for multi-level monitoring and deepen the understanding of Zn biology.
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| http://dx.doi.org/10.1016/j.cbpa.2023.102378 | DOI Listing |
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