currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus are highly pathogenic to humans. They cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome or hantavirus pulmonary syndrome (HCPS/HPS) in many countries. Some hantaviruses infect wild or domestic animals without causing severe symptoms. Rodents, shrews, and bats are reservoirs of various mammalian hantaviruses. Recent years have witnessed significant advancements in the study of hantaviruses including genomics, taxonomy, evolution, replication, transmission, pathogenicity, control, and patient treatment. Additionally, new hantaviruses infecting bats, rodents, shrews, amphibians, and fish have been identified. This review compiles these advancements to aid researchers and the public in better recognizing this zoonotic virus family with global public health significance.
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http://dx.doi.org/10.3390/v15081705 | DOI Listing |
J Adv Res
January 2025
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Centre, Zunyi Medical University, Zunyi, Guizhou, China. Electronic address:
Background: Neurodegenerative diseases (NDs) constitute a significant public health challenge, as they are increasingly contributing to global mortality and morbidity, particularly among the elderly population. Pathogenesis of NDs is intricate and multifactorial. Recently, post-transcriptional modifications (PTMs) of RNA, with a particular focus on mRNA methylation, have been gaining increasing attention.
View Article and Find Full Text PDFSci Total Environ
January 2025
Department of Biological and Agricultural Engineering, University of Arkansas, United States of America. Electronic address:
The increasing global demand for meat and dairy products, fueled by rapid industrialization, has led to the expansion of Animal Feeding Operations (AFOs) in the United States (US). These operations, often found in clusters, generate large amounts of manure, posing a considerable risk to water quality due to the concentrated waste streams they produce. Accurately mapping AFOs is essential for effective environmental and disease management, yet many facilities remain undocumented due to variations in federal and state regulations.
View Article and Find Full Text PDFActa Psychol (Amst)
January 2025
Research Institute of Business Analytics and Supply Chain Management, College of Management, Shenzhen University, Shenzhen, China. Electronic address:
The rise of social media has enabled unrestricted information sharing, regardless of its accuracy. Unfortunately, this has also resulted in the widespread dissemination of misinformation. This study aims to provide a comprehensive scientometric analysis under the PRISMA paradigm to clarify the repetitive trajectory of misinformation on social media in the current digital age.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Department of Occupational and Environmental Health, School of Public Health, Dalian Medical University, No. 9 West Section Lvshun South Road, Dalian 116044, China; Global Health Research Center, Dalian Medical University, No. 9 West Section Lvshun South Road, Dalian 116044, China. Electronic address:
Sodium arsenite (NaAsO), the most common form of inorganic arsenic prevalent in the environment, has been closely linked to islet β-cell dysfunction, a critical pathological hallmark of type 2 diabetes (T2D). Even though apoptosis plays a pivotal role in arsenic-induced islet β-cell dysfunction, the explicit underlying mechanisms remain elusive. Here, we have identified that the SET-Rac1 signaling pathway is instrumental in the apoptosis and dysfunction of islet β-cells induced by NaAsO.
View Article and Find Full Text PDFTalanta
January 2025
School of Pharmaceutical Sciences, Nanjing Tech University, 30th Puzhu South Road, Nanjing, 211816, China. Electronic address:
Cancer is one of the most fatal diseases threatening public health globally, and tumor metastasis causes greater than 90 % of cancer-associated deaths, presenting huge challenges for detection and efficient treatment of various human cancers. Cancer stem cells (CSCs) are a rare population of cancer cells and increasing evidences indicated CSCs are the driving force of tumor metastasis. In this study, a p-AuNSs-assisted single-cell Raman spectra has been established, to extract and amplify of CSCs fingerprints with single cell sensitivity.
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