Calcium messages in flagella are faster than messenger particles.

Calcium is one of the most versatile messengers for intracellular signaling. In the case of cilia and flagella calcium has the central role in transfer of communications between extracellular stimuli and intracellular formation of frequency modulated signal and their deciphering by target proteins. In this paper, the diffusion of fluorescently or otherwise tagged and un-tagged Ca particles is analyzed by solving the system of pertaining reaction-diffusion equations. We used Fourier transform tools to get asymptotic eigenfunctions for tagged (un-tagged) free and buffered Ca ions. We made some numerical estimations for diffusion coefficients corroborating the fact that messages diffuse faster than Ca messengers. From the best of our knowledge, this is the first time that Ca signaling in living cells is biophysically elaborated within the framework of model presented here. We suggest the experimental assay on the basis of radioactive Ca as tagged probe.