Comparisons of different treatment outcomes in IVF/ET patients with hydrosalpinx: a retrospective study.

Gynecol Endocrinol

Henan Provincial Obstetrical and Gynecological Diseases (Reproductive Medicine) Clinical Research Center, Center for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, P.R. China.

Published: December 2023

Aims: To explore suggestions for clinicians on the most effective treatment for hydrosalpinx undergoing IVF-ET.

Materials And Methods: We reviewed 936 women with hydrosalpinx and 6715 tubal infertile women without hydrosalpinx who underwent IVF/ICSI between January 2014 and August 2019 in our center. Hydrosalpinx patients received different treatments including laparoscopic surgery (only salpingectomy and proximal tubal occlusion/ligation were included), ultrasonic-guided aspiration and hysteroscopic tubal occlusion. Outcomes were analyzed by One-way ANOVA, Chi-Square test and logistic regression.

Results: The live birth rate (LBR) of laparoscopic surgery was significantly higher compared with hydrosalpinx aspiration (48.3% vs 39.6%,  = .024). The cumulative live birth rate (CLBR) of subsequent laparoscopic surgery was significantly higher compared with subsequent hysteroscopic occlusion (65.1% vs 34.1%,  = .001) and no subsequent treatment (65.1% vs 44.9%,   <  .005). Subsequent laparoscopic surgery significantly improved the CLBR of hydrosalpinx patients who received ultrasonic-guided aspiration and didn't get clinical pregnancy in fresh cycles (Odds Ratio (OR) =1.875; 95%CI = 1.041-3.378,  = .036).

Conclusions: Laparoscopic surgery leads to significantly higher LBR than ultrasonic-guided aspiration and significantly higher CLBR than hysteroscopic occlusion and no treatment.

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Source
http://dx.doi.org/10.1080/09513590.2023.2249999DOI Listing

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