AI Article Synopsis
- Ground-glass pulmonary nodules (GGNs) are typically biopsied using a method called percutaneous transthoracic biopsy, but this study focuses on the diagnostic yield of a newer approach using shape-sensing robotic-assisted bronchoscopy (ssRAB).
- In a retrospective analysis of 22 patients who underwent ssRAB from September 2021 to April 2023, the study found a high overall diagnostic yield of 87% for GGNs, with a sensitivity for malignancy of 88.9%.
- The results indicated that ssRAB is effective for diagnosing GGNs, including those with minimal solid components, and it has a low risk of procedure-related complications, with adenocarcinoma being the most frequently
Article Abstract
Background: Ground-glass pulmonary nodules (GGNs) are most commonly sampled by percutaneous transthoracic biopsy. Diagnostic yield for ground-glass nodules using robotic-assisted bronchoscopy has been scarcely described, with a reported yield of 70.6%.
Objectives: The aim of this study is to assess diagnostic yield for GGNs using shape-sensing robotic-assisted bronchoscopy (ssRAB).
Method: A retrospective study of patients who underwent ssRAB for evaluation of GGNs, from September 2021 to April 2023. Primary outcome was diagnostic yield of ssRAB for GGNs, secondary outcomes were sensitivity for malignancy, and complications that required admission or intervention.
Results: A total of 23 nodules were biopsied from 22 patients. Median age was 71 years (IQR 66-81), 63.6% were female, and 40.9% had a previous history of cancer. Forty-three percent of nodules were in the right upper lobes, and the median lesion size was 1.8 × 1.21. Twelve were subsolid nodules (SSNs), and 11 were pure GGNs. Overall diagnostic yield was 87%, with a sensitivity for malignancy of 88.9%. Adenocarcinoma was the most common malignancy diagnosed (70%). No procedure-related complications were reported.
Conclusion: The use of ssRAB shows a high diagnostic yield for diagnosing GGN and SSN with less than 6 mm solid component with a low risk for complications.
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| http://dx.doi.org/10.1159/000533314 | DOI Listing |
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