Illegal use of ractopamine (RAC) in the food industry has dire consequences for health which should be curbed by inexpensive on-site checks. In this study, four advanced nanostructures of AuNPs were examined for this purpose. For the first time, a novel cost-effective colorimetric opto-sensor based on gold nanoparticles in aqueous solution was developed and successfully utilized for the recognition of RAC in real samples. The colorimetric chemosensor based on AuNPs-CysA exhibited a linear range of 0.1 μM to 0.01 M with a limit of detection (LOD) of 0.001 μM. Also, using AuNPs-DDT as a photonic probe two ranges of linearity of 0.01 to 50 μM and 0.005 to 0.01 M were obtained (LOD = 1 nM). The outstanding features of the utilized nanostructures are the simple preparation, the suitable stability of AuNPs-CysA and the excellent selectivity of AuNPs-DDT toward RAC recognition. Finally, the engineered colorimetric systems were combined with a simple and inexpensive optimized microfluidic glass fiber-based device. This work paves the way for devising inexpensive and efficient on-site recognition devices for food safety checks.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d3ay01064c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
DNA Tetrahedron Reformative Lateral Flow Assay for Improved Detection Sensitivity and Anti-Interference.
Langmuir
January 2025
School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
The lateral flow assay is a strip-based analytical method for the portable and convenient detection of analytes of interest. It has the advantages of visual observation, autonomous sample flow, fast coloration time, minimal tedious operation procedures, and reliance on specialized instruments. However, the rough surface of the nitrocellulose membrane renders it difficult for the immobilized nucleic acids to remain in an ordered arrangement, and the immobilized nucleic acids are also liable to be digested in a complex matrix, inducing limited sensitivity and anti-interference.
View Article and Find Full Text PDFN-Doped Carbon Nanodots as Temperature Sensors and Fluorescent Probes for the Detection of Tinidazole in Milk.
J Fluoresc
January 2025
School of Science, Jiangnan University, Wuxi, 214122, China.
In this study, nitrogen-doped carbon nanodots (N-CDs) with temperature and fluorescence sensing were prepared via hydrothermal method using L-lysine and ethylenediamine as precursors. The synthesized N-CDs exhibited spherical morphology with sizes ranging from 2.8 to 5.
View Article and Find Full Text PDFSmartphone-assisted hydrogel sensing platform based on double emission carbon dots for portable on-site tetracycline detection.
Mikrochim Acta
January 2025
Department of Chemistry and Material Engineering, Lyuliang University, Lyuliang, 033000, P. R. China.
Innovative double-emission carbon dots (DE-CDs) were synthesized via a one-step hydrothermal method using fennel and m-phenylenediamine (m-PD) as precursors. These DE-CDs exhibited dual emission wavelengths at 432 and 515 nm under different excitations, making them highly versatile for fluorescence-based applications. The fluorescence of the DE-CDs was efficiently quenched by tetracycline (TC) through the inner filter effect (IFE), allowing for the construction of a sensitive dual-response fluorescent sensor.
View Article and Find Full Text PDFMicrobe-mediated synthesis of defect-rich CeO nanoparticles with oxidase-like activity for colorimetric detection of L-penicillamine and glutathione.
Nanoscale
January 2025
College of Biotechnology and Pharmaceutical Engineering, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211816, P.R. China.
To enhance production efficiency, curtail costs, and minimize environmental impact, developing simple and sustainable nanozyme synthesis methods has been the focus of relevant research. In this report, graphite-coated CeO nanoparticles (CeO NPs) with multiple defects (Ce defects, oxygen vacancies and carbon defects) were synthesized the culture filtrate of the extremely radioresistant bacterium R12 ( R12). The as-prepared CeO NPs exhibit remarkable oxidase (OXD)-like activity, efficiently catalyzing the oxidation of the chromogenic substrate 3,3',5,5'-tetramethylbenzidine (TMB) to form oxTMB, even in the absence of HO.
View Article and Find Full Text PDFOptimizing Exclusion Criteria for Clinical Trials of Persistent Lyme Disease Using Real-World Data.
Healthcare (Basel)
December 2024
Union Square Medical Associates, 595 Buckingham Way, Suite 350, San Francisco, CA 94132, USA.
Background/objectives: Although eligibility criteria for clinical trials significantly impact study outcomes, these criteria are often established without scientific justification, leading to delayed recruitment, small sample sizes, and limited study generalizability. Persistent Lyme disease (PLD) presents unique challenges due to symptom variability, inconsistent treatment responses, and the lack of reliable biomarkers, underscoring the need for scientifically justified eligibility criteria.
Objective: This study examines the effects of commonly used enrollment criteria on sample yield in PLD clinical trials using real-world data (RWD) from the MyLymeData patient registry.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!