AI Article Synopsis
- There is growing scientific interest in the neurobiological changes that occur during pregnancy and motherhood, particularly in first-time mothers.
- Around labor time, these mothers experience specific neuroanatomical changes that are closely related to behaviors associated with being a parent.
- The review explores the relationship between pregnancy hormones, brain plasticity mechanisms, and maternal behavior, providing a framework for future research in this area.
Article Abstract
We are witnessing a stark increase in scientific interest in the neurobiological processes associated with pregnancy and maternity. Convergent evidence suggests that around the time of labour, first-time mothers experience a specific pattern of neuroanatomical changes that are associated with maternal behaviour. Here we provide an overview of the human neurobiological adaptations of motherhood, focusing on the interplay between pregnancy-related steroid and peptide hormones, and neuroplasticity in the brain. We discuss which brain plasticity mechanisms might underlie the structural changes detected by MRI, which hormonal systems are likely to contribute to such neuroanatomical changes and how these brain mechanisms may be linked to maternal behaviour. This Review offers an overarching framework that can serve as a roadmap for future investigations.
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| http://dx.doi.org/10.1038/s41583-023-00733-6 | DOI Listing |
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