AI Article Synopsis

  • * Traditional biomarkers and tests for detecting cardiac issues, like troponins and ECG, have limited effectiveness in advanced CKD; alternative methods such as dobutamine stress echocardiography and myocardial scintigraphy are more reliable.
  • * Techniques for assessing heart structure and function vary in complexity and cost, while also monitoring heart rhythm through ambulatory methods helps diagnose arrhythmias; standardized blood pressure protocols are recommended for managing hypertension in CKD patients.

Article Abstract

Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD) and cardiovascular death. Identifying and monitoring cardiovascular complications and hypertension is important for managing patients with CKD or kidney failure and transplant recipients. Biomarkers of myocardial ischaemia, such as troponins and electrocardiography (ECG), have limited utility for diagnosing cardiac ischaemia in patients with advanced CKD. Dobutamine stress echocardiography, myocardial perfusion scintigraphy and dipyridamole stress testing can be used to detect coronary disease in these patients. Left ventricular hypertrophy and left ventricular dysfunction can be detected and monitored using various techniques with differing complexity and cost, including ECG, echocardiography, nuclear magnetic resonance, CT and myocardial scintigraphy. Atrial fibrillation and other major arrhythmias are common in all stages of CKD, and ambulatory heart rhythm monitoring enables precise time profiling of these disorders. Screening for cerebrovascular disease is only indicated in asymptomatic patients with autosomal dominant polycystic kidney disease. Standardized blood pressure is recommended for hypertension diagnosis and treatment monitoring and can be complemented by ambulatory blood pressure monitoring. Judicious use of these diagnostic techniques may assist clinicians in detecting the whole range of cardiovascular alterations in patients with CKD and enable timely treatment of CVD in this high-risk population.

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41581-023-00747-4DOI Listing

Publication Analysis

Top Keywords

disease patients
12
kidney disease
12
cardiovascular disease
8
patients chronic
8
chronic kidney
8
patients ckd
8
left ventricular
8
blood pressure
8
disease
7
patients
7

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!