AI Article Synopsis

  • The study evaluated malnutrition prevalence and risk factors in head and neck cancer patients undergoing radiotherapy.
  • 108 patients were assessed using the Nutritional Risk Screening-2002 tool, with analysis of sociodemographic and laboratory data influencing nutrition status.
  • Key findings indicated older age, late tumor stage, neck radiotherapy site, diabetes, and mental health issues (anxiety and depression) significantly increased nutritional risk, emphasizing the need for early identification for better nutritional interventions.

Article Abstract

Objective: In this study, we investigated the prevalence of malnutrition and analyzed the related factors among patients with head and neck cancer (HNC) undergoing radiotherapy.

Methods: We included 108 patients with head and neck cancer undergoing radiotherapy from the oncology and thoracic surgery departments of a comprehensive medical center in Qingdao between January 2019 and June 2020. We used the Nutritional Risk Screening-2002 tool (NRS-2002) to evaluate their nutritional status during radiotherapy. We analyzed the basic sociodemographic information and laboratory indicators of the respondents to examine the impact of these factors on nutritional status.

Results: In the 108 patients that we studied, those aged ≥65 years had a significantly higher nutritional risk when compared to patients <65 years of age (P < 0.05). Univariate analysis revealed that a late tumor stage (P = 0.039), the neck being the site of radiotherapy (P = 0.009), the presence of diabetes (P < 0.001), and the presence of anxiety and depression (P = 0.002) were associated with nutritional risks for patients with head and neck cancer undergoing radiotherapy. Multivariate logistic regression analysis identified a late tumor stage, the neck being the radiotherapy site, and combined anxiety and depression as nutritional risk factors in such patients.

Conclusion: We found a high incidence of malnutrition in patients undergoing radiotherapy for HNC; this highlights the importance of early identification of patients at risk and evaluation of related risk factors to enhance the efficacy of nutritional interventions.

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http://dx.doi.org/10.1016/j.ejon.2023.102387DOI Listing

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