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The role of hospital pharmacists in supporting the appropriate and safe use of CGT/ATMPs: a scoping review of current insights.
BMC Health Serv Res
January 2025
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Background: The role of hospital pharmacists in managing cell and gene therapy (CGT) and advanced therapy medicinal products (ATMPs) is gradually being recognized but the evidence about impact of their role has not been systematically reported.
Objective: This study was aimed to summarize the professional services provided by hospital pharmacists on managing CGT/ATMPs and the evidence about the effects on patient care, as well as to identify the perceptions about pharmacists assuming a role that supports the appropriate and safe use of CGT/ATMPs.
Methods: Literature from 4 electronic databases (PubMed, ScienceDirect, Web of Science, Scopus) were searched following PRISMA checklist to yield publications on the interventions provided by hospital pharmacists in the management of CGT/ATMPs dated since 1 January 2013 till 30 April 2023.
A protocol to study the effect of targeted parental education intervention to identify early childhood development disorder - multisite interventional study.
Arch Public Health
January 2025
Community Medicine, ESIC Medical College & Hospital, K.K. Nagar, Chennai, 600078, India.
Background: In India, approximately 3.5 million children are affected by Developmental Delay (DD), often stemming from preterm births. These delays contribute to neurological and motor development delays, placing a significant financial burden on families.
View Article and Find Full Text PDFProposed framework for the integration of refractive error services into the eye health ecosystem in Kenya via social enterprise.
Sci Rep
January 2025
College of Health Sciences, Department of Optometry, University of KwaZulu-Natal, Durban, South Africa.
The global burden of uncorrected refractive error demands for adoption of different approaches inclined towards scaling effective refractive error coverage. While innovative approaches such as utilization of telemedicine is being adopted by social enterprises in different parts of the world to scale refractive error service delivery, commercial entrepreneurship still dominates the optical industry in Kenya with minimal focus on accessibility and affordability. However, to achieve effective refractive error coverage across the economic pyramid, integration of enterprises inclined towards fulfilling a social mission through innovative approaches such as telemedicine is desirable.
View Article and Find Full Text PDFCombination of plasma acoustic emission signal and laser-induced breakdown spectroscopy for accurate classification of steel.
Anal Chim Acta
January 2025
Key Laboratory of High Performance Manufacturing for Aero Engine (MIIT), Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, China. Electronic address:
Background: Fast and accurate classification of steel can effectively improve industrial production efficiency. In recent years, the use of laser-induced breakdown spectroscopy (LIBS) in conjunction with other techniques for material classification has been developing. Plasma Acoustic Emission Signal (PAES) is a type of modal information separate from spectra that is detected using LIBS, and it can reflect some of the sample's physicochemical information.
View Article and Find Full Text PDFDecoding Complexity: The Role of Long-Read Sequencing in Unraveling Genetic Disease Etiologies.
Mutat Res Rev Mutat Res
January 2025
State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing Institute of Radiation Medicine, Beijing 100850, People's Republic of China; School of Life Sciences, Hebei University, No. 180 Wusi Dong Road, Lian Chi District, Baoding City, Hebei Province 071000, China. Electronic address:
In recent years, next-generation high-throughput sequencing technology has been widely used in clinical practice for the identification and diagnosis of Mendelian diseases as an auxiliary detection method. Nevertheless, due to the limitations in read length and poor coverage of complex genomic regions, the etiology of many genetic diseases is unclear. Long-read sequencing (LRS) addresses these limitations of next-generation sequencing.
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