AI Article Synopsis
- Scientists studied the size of genes in different Drosophila (fruit fly) species and found big differences, with one fly having about 3 times more genetic material than another.
- They discovered that a specific part of the gene (the Muller F element) can be much bigger in some species, going from 1.3 Mb to over 18 Mb.
- The researchers created detailed genetic maps for 4 types of Drosophila with bigger Muller F elements, which will help us understand why some genes are larger and what that means for evolution.
Article Abstract
Flow cytometry estimates of genome sizes among species of Drosophila show a 3-fold variation, ranging from ∼127 Mb in Drosophila mercatorum to ∼400 Mb in Drosophila cyrtoloma. However, the assembled portion of the Muller F element (orthologous to the fourth chromosome in Drosophila melanogaster) shows a nearly 14-fold variation in size, ranging from ∼1.3 Mb to >18 Mb. Here, we present chromosome-level long-read genome assemblies for 4 Drosophila species with expanded F elements ranging in size from 2.3 to 20.5 Mb. Each Muller element is present as a single scaffold in each assembly. These assemblies will enable new insights into the evolutionary causes and consequences of chromosome size expansion.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542312 | PMC |
| http://dx.doi.org/10.1093/g3journal/jkad191 | DOI Listing |
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