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Ventricular tachycardia ablation across age groups: Outcomes, trends and demographics. Insights from the National Inpatient Sample Database.
Heart Rhythm O2
December 2024
Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania.
Background: Ventricular tachycardia ablation (VTA) is an important treatment option for ventricular tachycardia, with increasing use across all age groups. However, age-related differences in outcomes remain a concern.
Objective: This study aimed to investigate age-related trends in VTA procedures and their associated adverse events across the United States from 2011 to 2021.
Changes in the copy number of large genomic regions, termed copy number variations (CNVs), contribute to important phenotypes in many organisms. CNVs are readily identified using conventional approaches when present in a large fraction of the cell population. However, CNVs that are present in only a few genomes across a population are often overlooked but important; if beneficial under specific conditions, a de novo CNV that arises in a single genome can expand during selection to create a larger population of cells with novel characteristics.
View Article and Find Full Text PDFRole of risk alleles in the pathogenesis of neovascular age-related macular degeneration.
Taiwan J Ophthalmol
January 2024
NHO Tokyo Medical Center, National Institute of Sensory Organs, Tokyo, Japan.
Age-related macular degeneration (AMD) is one of the leading causes of severe irreversible blindness worldwide in the elderly population. AMD is a multifactorial disease mainly caused by advanced age, environmental factors, and genetic variations. Genome-wide association studies (GWAS) have strongly supported the link between locus on chromosome 10q26 and AMD development, encompassing multiple variants, rs10490924 (c.
View Article and Find Full Text PDFVariations in linear energy transfer distributions within a European proton therapy planning comparison of paediatric posterior fossa tumours.
Phys Imaging Radiat Oncol
October 2024
Aarhus University Hospital, Danish Centre for Particle Therapy, Aarhus N, Denmark.
Background And Purpose: Radiotherapy for paediatric posterior fossa tumours may cause complications in the brainstem and upper spinal cord due to high doses. With proton therapy (PT) this risk may increase due to higher relative biological effectiveness (RBE) from elevated linear energy transfer (LET). This study assesses variations in LET in the brainstem and spinal cord in proton treatment plans from European centres.
View Article and Find Full Text PDFis an important spice and medicinal plant widely utilized in East and Southeast Asia. Non-targeted metabolomics techniques were employed to study the variations in the content and composition of essential oil from during drying at different temperatures: 40°C, 50°C, 60°C, and 70°C. A total of 260 metabolites were detected using gas chromatography-mass spectrometry (GC-MS), mainly terpenoids and aldehydes.
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