Rickettsial infection, known as Rocky Mountain spotted fever, is a challenging diagnosis as early clinical manifestations are difficult to distinguish from viral illnesses. Symptoms at presentation depend on the organs involved, ranging from a skin rash as evidence of vascular damage to prerenal azotemia, respiratory failure, hepatic injury, or encephalitis. We report an unusual case of an otherwise healthy 83-year-old female whose serologies tested positive for , which led to cardiac dysrhythmia, i.e., the new onset of atrial fibrillation associated with conversion pauses. The patient was treated with antibiotics and ultimately underwent permanent pacemaker placement with resolution. This case highlights cardiac dysrhythmia as a late and severe manifestation in patients diagnosed with rickettsial illness.
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http://dx.doi.org/10.7759/cureus.42288 | DOI Listing |
Ecol Lett
January 2025
Rocky Mountain Biological Laboratory, Gothic, Colorado, USA.
It is unclear how environmental change influences standing genetic variation in wild populations. Here, we characterised environmental conditions that protect versus erode polymorphic chemical defences in Boechera stricta (Brassicaceae), a short-lived perennial wildflower. By manipulating drought and herbivory in a 4-year field experiment, we measured the effects of driver variation on vital rates of genotypes varying in defence chemistry and then assessed interacting driver effects on total fitness (estimated as each genotype's lineage growth rate, λ) using demographic models.
View Article and Find Full Text PDFBur., a versatile plant with medicinal, edible, landscaping, and ecological applications, holds significant economic value and boasts a long-standing history of utilization in China. Despite its robust adaptability, rapid growth, and extensive distribution, the current research gap concerning the physiological mechanisms underlying stem cutting propagation hampers the development of efficient strategies for commercial-scale propagation of , particularly for large-scale cultivation.
View Article and Find Full Text PDFTransgend Health
December 2024
Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA.
Injectable estrogens are options for gender-affirming hormone therapy per guidelines, which suggest intramuscular dosages of 5-30 mg every 2 weeks or 2-10 mg weekly with estradiol cypionate or valerate interchangeably. Data among transgender and gender-diverse patients are limited due to local unavailability and concerns around laboratory assay variability and estradiol (E2) level fluctuation. We note a concerning trend where patients are prescribed high-dose injections based on the guidelines leading to serum E2 levels well above the range recommended in the same guidelines.
View Article and Find Full Text PDFPeerJ
December 2024
College of Forestry, Central South University of Forestry and Technology, Changsha, Hunan, China.
In this study, experiments were conducted on soil samples collected from depths of 0-15 cm, 15-30 cm, and 30-50 cm at the National Long-term Scientific Research Base for the Comprehensive Management of Rocky Desertification in the Wuling Mountains. The aim was to determine the physicochemical indexes and explore the nature and spatial heterogeneity of the soil of the planted mixed forests within the rocky desertification area of the Wuling Mountain. Various analytical methods were employed, including descriptive statistical analysis, correlation analysis, analysis of variance, principal component analysis, spatial interpolation analysis, and kriging interpolation, to fit the optimal model of the semi-variance function of soil physicochemical properties and analyze the model's parameters.
View Article and Find Full Text PDFFront Neurol
December 2024
Brain Rehabilitation Research Center, Malcom Randall Department of Veterans Affairs Medical Center, North Florida/South Georgia Veterans Health System, Gainesville, FL, United States.
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