Urolithiasis, commonly known as kidney stones, is characterized by the formation of hard deposits in the urinary tract. These stones can cause severe pain and discomfort, and their management typically involves a combination of medical interventions and lifestyle modifications. According to the literature, 30% and 50% of urolithiasis cases recur. Between 9 and 12% of persons in industrialised countries are predicted to have urolithiasis at some time. Due to the high frequency of stone formation, recurrent nature, and prevalence in adults, it has a significant impact on society, the person, and the health care system. Adopting the best prophylactic measures is crucial in light of these developments to decrease the impact of urolithiasis on individuals and society. In recent years, there has been growing interest in the potential role of nutraceuticals in the management of urolithiasis. Nutraceuticals, such as herbal extracts, vitamins, minerals, and probiotics, have gained recognition for their potential in promoting urinary health and reducing the risk of urolithiasis. These compounds can aid in various ways, including inhibiting crystal formation, enhancing urine pH balance, reducing urinary calcium excretion, and supporting kidney function. Additionally, nutraceuticals can help alleviate symptoms associated with urolithiasis, such as pain and inflammation. While medical interventions remain crucial, incorporating nutraceuticals into a comprehensive management plan can offer a holistic approach to urolithiasis, improving patient outcomes and quality of life. Therefore, nutraceuticals may be a desirable choice for treating and avoiding recurring urolithiasis for patients and medical professionals. Therefore, the present study has focused on nutraceuticals' role in preventing urolithiasis.
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http://dx.doi.org/10.2174/1389201024666230821122416 | DOI Listing |
Int J Mol Sci
January 2025
Nursing Department, College of Staten Island, City University of New York, Staten Island, NY 10314, USA.
Kidney stones typically present as renal colic in emergency departments (EDs), where patients experience severe pain and often require parenteral therapy for symptom management. The economic burden associated with managing kidney stones exceeds USD 5 billion annually in the US and accounts for more than a million visits to EDs each year. There is clear evidence emphasizing the need for innovative and alternative pain control options for patients with renal colic.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Epidemiology and Health Statistics, School of Public Health and Health Management, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
To analyze the relationship between hot or cold, and wet or dry interacting weather, and urolithiasis-related hospitalizations. Distributed lag nonlinear model for time series design was used to build exposure-response curves for the association of daily mean temperature and relative humidity with urolithiasis-related hospitalizations. Cut-off values were determined for temperature, humidity, and dichotomous categories to define heat-cold and wet-dry meteorological conditions.
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January 2025
Department of Endocrine, People's Hospital of Chongqing Liang Jiang New Area, Chongqing, China.
The negative effects of lead exposure on human health have attracted widespread attention. Our present study focused on assessing the relationship between urinary lead levels (ULL) and the risk of kidney stones in US adults. We used data from NHANES 2007-2018 for this cross-sectional study, where participants had complete data on ULL and kidney stones.
View Article and Find Full Text PDFUrolithiasis
January 2025
Department of Urology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109-5330, USA.
Understanding renal pelvis pressure (P) during ureteroscopy (URS) has become increasingly important. High irrigation rates, desirable to maintain visualization and limit thermal dose, can increase P. Use of a multi-channel ureteroscope (m-ureteroscope) with a dedicated drainage channel is one strategy that may facilitate simultaneous low P and high flowrate.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
The Department of Clinical Laboratory, Zhejiang Hospital, Hangzhou, China.
Rationale: Gitelman syndrome (GS) is a rare hereditary electrolyte disorder caused by mutations in the SLC12A3 gene. There is limited literature on the role of hydrochlorothiazide (HCT) testing and the SLC12A3 single heterozygous mutation in the diagnosis and management of patients with GS. In addition, cases of GS with concomitant kidney stones are rare.
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