Surgical site infection following surgery for hand trauma: a systematic review and meta-analysis.

J Hand Surg Eur Vol

Kadoorie Centre for Critical Care Research and Education, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK.

Published: November 2023

AI Article Synopsis

  • * A systematic review and meta-analysis assessed the risk of SSI in hand trauma surgeries, analyzing 201 studies involving over 315,000 patients, with findings indicating a 10% infection risk in randomized trials and a 5% overall risk across all studies.
  • * These findings can inform clinical practices, such as aiding in informed consent discussions, fostering shared decision-making, and guiding future trials for antimicrobial treatments in hand trauma cases.

Article Abstract

Surgical site infection is the most common healthcare-associated infection. Surgical site infection after surgery for hand trauma is associated with increased antibiotic prescribing, re-operation, hospital readmission and delayed rehabilitation, and in severe cases may lead to amputation. As the risk of surgical site infection after surgery for hand trauma remains unclear, we performed a systematic review and meta-analysis of all primary studies of hand trauma surgery, including randomized controlled trials, cohort studies, case-control studies and case series. A total of 8836 abstracts were screened, and 201 full studies with 315,618 patients included. The meta-analysis showed a 10% risk of surgical site infection in randomized control trials, with an overall risk of 5% when all studies were included. These summary statistics can be used clinically for informed consent and shared decision making, and for power calculations for future clinical trials of antimicrobial interventions in hand trauma.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616993PMC
http://dx.doi.org/10.1177/17531934231193336DOI Listing

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