Investigating the effect of selenium nano-particles on microbial activity and cancerous cell line of MCF-7 and MDA-MB-231.

Selenium is a mineral that is essential to human health and is widely recognized for its responsibilities as a powerful anticancer vitamin and antibacterial vitamin. Selenium also plays a critical part in the production of vitamin D. The purpose of this research was to evaluate the particular effects that selenium nano-particles (SeNPs') had on the infectious agent Staphylococcus aureus as well as the breast cancer cell lines MCF-7 and MDA-MB-231. The proportion of MDA-MB-231 and MCF-7 cells that underwent late apoptosis was dramatically increased by selenium nanoparticles, whereas the number of cells that underwent cell expansion was significantly reduced. There was a wide range of variability in the effects of selenium nanoparticle treatment on cell growth apoptosis, apoptosis rates and patterns of cell cycle arrest. After 2, 4 and 6 hours, researchers found that the development of S. aureus was significantly reduced by selenium nanoparticles at doses of 8.0, 16.0 and 32g/mL. In addition to this, the presence of selenium nanoparticles resulted in a reduced percentage of bacteria that were still alive. According to the findings of the study, there is a need for more research into selenium nanoparticles with the intention of preventing and treating infections caused by S. aureus.