Myotendinous junction is the transition zone between the muscle and its tendon. Hence, it is subject to immense stress within the muscle. In this study, it is found that muscles having a greater tensile have a more arranged myotendinous junction compared to muscles with lesser tensile strength. Cadaveric specimens - plantaris, gastrocnemius, and soleus have been histologically studied to study the same.
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http://dx.doi.org/10.7759/cureus.42233 | DOI Listing |
BMC Musculoskelet Disord
January 2025
Department of Hand Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
Background: Rupture of extensor pollicis longus tendon (EPL) is a known complication following a distal radius fracture (DRF). Although the precise mechanisms behind these ruptures remain unclear, vascular impairment is thought to play a significant role. Additionally, the impact of an EPL rupture on microstructure of the tendon and muscle is not well understood, but such information could be important in guiding treatment strategies.
View Article and Find Full Text PDFJ Cell Sci
December 2024
Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
The myotendinous junction (MTJ) is a weak link in the musculoskeletal system. Here, we isolated the tips of single myofibres from healthy human hamstring muscles for confocal microscopy (n=6) and RNAscope in situ hybridisation (n=6) to gain insight into the profiles of cells and myonuclei in this region, in a fibre type manner. A marked presence of mononuclear cells was observed coating the myofibre tips (confirmed by serial block face scanning electron microscopy and cryosection immunofluorescence), with higher numbers for type I (median 29; range 16-63) than type II (16; 9-23) myofibres (p<0.
View Article and Find Full Text PDFRev Bras Ortop (Sao Paulo)
October 2024
Serviço de Ortopedia e Traumatologia, Hospital São Vicente de Paulo/Instituto de Ortopedia e Traumatologia, Passo Fundo, RS, Brasil.
Arch Plast Surg
November 2024
Department of Plastic and Reconstructive Surgery, Gwangmyeong Sungae General Hospital, Gwangmyeong, Korea.
Skelet Muscle
November 2024
UMR7622, Developmental Biology Laboratory, Sorbonne Université, Institut Biologie Paris Seine, CNRS, Inserm U1156, Paris, 75005, France.
Skeletal muscle formation involves tight interactions between muscle cells and associated connective tissue fibroblasts. Every muscle displays the same type of organisation, they are innervated in the middle and attached at both extremities to tendons. Myonuclei are heterogeneous along myotubes and regionalised according to these middle and tip domains.
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