AI Article Synopsis

  • IPMNs are growths in the pancreas that can lead to cancer, and doctors often remove them to check for cancer risk.
  • Researchers reviewed important topics related to examining these growths in patients who had surgery.
  • The study offers new ideas on how to categorize and understand IPMNs better to help doctors make better treatment decisions.

Article Abstract

Background: Intraductal papillary mucinous neoplasms (IPMNs) are a cystic precursor to pancreatic cancer. IPMNs deemed clinically to be at high-risk for malignant progression are frequently treated with surgical resection, and pathological examination of the pancreatectomy specimen is a key component of the clinical care of IPMN patients.

Methods: Systematic literature reviews were conducted around eight topics of clinical relevance in the examination of pathological specimens in patients undergoing resection of IPMN.

Results: This review provides updated perspectives on morphological subtyping of IPMNs, classification of intraductal oncocytic papillary neoplasms, nomenclature for high-grade dysplasia, assessment of T stage, distinction of carcinoma associated or concomitant with IPMN, role of molecular assessment of IPMN tissue, role of intraoperative assessment by frozen section, and preoperative evaluation of cyst fluid cytology.

Conclusions: This analysis provides the foundation for data-driven approaches to several challenging issues in the pathology of IPMNs.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pan.2023.08.002DOI Listing

Publication Analysis

Top Keywords

challenging issues
8
issues pathology
8
intraductal papillary
8
papillary mucinous
8
mucinous neoplasms
8
systematic review
4
review challenging
4
pathology intraductal
4
neoplasms background
4
background intraductal
4

Similar Publications

GradeDiff-IM: An Ensembles Model-based Grade Classification of Breast Cancer.

Biomed Phys Eng Express

January 2025

School of Engineering and Computing, University of the West of Scotland, University of the West of Scotland - Paisley Campus, Paisley PA1 2BE, UK, City, Paisley, PA1 2BE, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

Cancer grade classification is a challenging task identified from the cell structure of healthy and abnormal tissues. The partitioner learns about the malignant cell through the grading and plans the treatment strategy accordingly. A major portion of researchers used DL models for grade classification.

View Article and Find Full Text PDF

How and why funders support engaged research.

Proc Natl Acad Sci U S A

January 2025

Ewing Marion Kauffman Foundation, Kansas City, MO 64110.

Research that better aligns policy, practice, and research communities is gaining momentum around the world. This includes engaged research strategies that bring partners, and their diverse perspectives and kinds of knowledge, together to shape research agendas with on-the-ground-needs and to create dynamic problem-solving processes. These approaches aim to generate more equitable and effective solutions to societal challenges.

View Article and Find Full Text PDF

Background: Objective structured clinical examinations (OSCEs) are a widely recognized and accepted method to assess clinical competencies but are often resource-intensive.

Objective: This study aimed to evaluate the feasibility and effectiveness of a virtual reality (VR)-based station (VRS) compared with a traditional physical station (PHS) in an already established curricular OSCE.

Methods: Fifth-year medical students participated in an OSCE consisting of 10 stations.

View Article and Find Full Text PDF

Background: Due to advances in treatment, HIV is now a chronic condition with near-normal life expectancy. However, people with HIV continue to have a higher burden of mental and physical health conditions and are impacted by wider socioeconomic issues. Positive Voices is a nationally representative series of surveys of people with HIV in the United Kingdom.

View Article and Find Full Text PDF

Background: Bangladesh and West Bengal, India, are 2 densely populated South Asian neighboring regions with many socioeconomic and cultural similarities. In dealing with breast cancer (BC)-related issues, statistics show that people from these regions are having similar problems and fates. According to the Global Cancer Statistics 2020 and 2012 reports, for BC (particularly female BC), the age-standardized incidence rate is approximately 22 to 25 per 100,000 people, and the age-standardized mortality rate is approximately 11 to 13 per 100,000 for these areas.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!