The conservation of gene models can support genome annotation.

Plant Genome

School of Biological Sciences and Institute of Agriculture, University of Western Australia, Perth, Western Australia, Australia.

Published: September 2023

Many genome annotations include false-positive gene models, leading to errors in phylogenetic and comparative studies. Here, we propose a method to support gene model prediction based on evolutionary conservation and use it to identify potentially erroneous annotations. Using this method, we developed a set of 15,345 representative gene models from 12 legume assemblies that can be used to support genome annotations for other legumes.

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Source
http://dx.doi.org/10.1002/tpg2.20377DOI Listing

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