AI Article Synopsis
- SARS-CoV-2 infection can lead to a systemic inflammatory response, affecting multiple organs, with immunoglobulin A (IgA) playing a significant role in this process.
- A rare complication of COVID-19, Henoch-Schönlein purpura (HSP), was observed in a 23-year-old woman one week post COVID-19 diagnosis, presenting symptoms such as abdominal pain, joint pain, and skin rashes.
- Treatment with intravenous methylprednisolone, followed by oral prednisone, resulted in significant clinical improvement without any lasting kidney issues.
Article Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can affect multiple organs due to activation of an inflammatory response. One of the key components of this response is the activation of immunoglobulin A (IgA), thus causing endothelial injury and inflammation. Henoch-Schönlein purpura (HSP) has been rarely reported in adult patients as a complication of the coronavirus disease 2019 (COVID-19) infection. In this report, we present a case of HSP occurring one week after the diagnosis of COVID-19 in a 23-year-old woman. Her symptoms included nausea, vomiting, diffused abdominal pain, joint pain, hematuria, and palpable purpura of the lower extremities. She was treated with intravenous methylprednisolone sodium succinate, followed by oral prednisone therapy, which resulted in clinical improvement, including resolution of abdominal and joint pain as well as skin rashes, without remaining renal complication.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433697 | PMC |
| http://dx.doi.org/10.7759/cureus.42063 | DOI Listing |
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