AI Article Synopsis
- Primary myelofibrosis (PMF) and polycythaemia vera (PV) are uncommon blood disorders that can lead to serious complications like blood clots, bleeding, and potentially cancer.
- These conditions exhibit diverse biological and clinical characteristics, making their management in everyday medical practice quite variable.
- The review offers a recent perspective on diagnosing, predicting outcomes, and treating PMF and PV, highlighting how a group of experts in France applies research findings to standard healthcare practices.
Article Abstract
Primary myelofibrosis (PMF) and polycythaemia vera (PV) are rare -negative myeloproliferative neoplasms, associated with an increased risk of thrombosis, haemorrhagic complications and progression to fibrosis or leukaemia or fibrosis for PV. Both diseases are characterised by biological and clinical heterogeneity, leading to great variability in their management in routine clinical practice. In this review, we present an updated overview of the diagnosis, prognosis and treatment of PMF and PV, and we discuss how our multidisciplinary expert group based across France translates this evidence-based knowledge into routine clinical practice.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435696 | PMC |
| http://dx.doi.org/10.1002/jha2.734 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pathological features of the differentiation landscape in esophageal squamous cell cancer and their correlations with prognosis.
Front Oncol
December 2024
Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Background: For esophageal squamous cell carcinoma (ESCC), universally accepted pathological criteria for classification by differentiation degree are lacking. Tumor budding, single-cell invasion, and nuclear grade, recognized as prognostic factors in other carcinomas, have rarely been investigated for their correlation with differentiation and prognosis in ESCC. This study aims to determine if pathological findings can predict differentiation degree and prognosis in ESCC.
View Article and Find Full Text PDFA Single-Center Retrospective Study on the Clinical Outcomes of TightRope Fixation Versus Syndesmotic Screw Fixation in the Management of Acute Traumatic Ankle Syndesmotic Injuries.
Cureus
December 2024
Trauma and Orthopaedics, Buckinghamshire Healthcare NHS Trust, Aylesbury, GBR.
Background Ankle fractures are one of the most common presentations in orthopaedic surgery and represent the third most frequent musculoskeletal injury in the elderly population. Syndesmotic injuries can be associated with ankle fractures, and surgical intervention is critical in these injuries to restore stability and prevent long-term disability. Traditionally, syndesmotic screw fixation has been the standard treatment for acute traumatic syndesmotic injuries, but controversies regarding this fixation method remain.
View Article and Find Full Text PDFIntroducing entrustable professional activities for postgraduate medical training in Switzerland.
GMS J Med Educ
November 2024
University of Bern, Institute for Medical Education, Department for Assessment and Evaluation, Bern, Switzerland.
Introduction: Graduate medical education is being reformed in many countries, with a focus on the principles of competency-based medical education (CBME). A main novel aspect in this context is the implementation of entrustable professional activities (EPAs). The introduction of EPAs aims to better align training curricula with clinical practice, provide individualized supervision, and enhance the quality of feedback.
View Article and Find Full Text PDFIdentification of Core Interprofessional Preceptor Competencies and Development of a Preceptor Self-Assessment Tool.
SAGE Open Nurs
December 2024
School of Nursing, University of Washington, Seattle, WA, USA.
Objective: The purpose of this study was to determine what activities and skills interprofessional health science preceptors (IHSPs) perform and value as a part of their pedagogical practice in order to support the development of a preceptor self-assessment tool and assist in preceptor training.
Methods: We administered an online survey to identify core preceptor activities across health sciences disciplines that interact with nursing. The initial survey items were developed based on the Interprofessional Education Collaborative (IPEC) core competencies as well as a search of literature on expected preceptor competencies and activities across individual health sciences professions.
Acquired methemoglobinemia in infancy secondary to diarrhea: a case report.
Pan Afr Med J
September 2024
Al Jalila Children's Hospital, Dubai Health, Dubai, United Arab Emirates.
Methemoglobinemia (MetHb) is a life-threatening condition that reduces the oxygen-carrying ability of hemoglobin. Acquired methemoglobinemia usually results from exposure to specific oxidizing agents. Symptoms and complications depend on the MetHb level, which can sometimes be fatal.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!