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Crystal-structure determination and Hirshfeld surface analysis of two new thio-phene derivatives: ()--{2-[2-(benzo[]thio-phen-2-yl)ethen-yl]-5-fluoro-phen-yl}benzene-sulfonamide and ()--{2-[2-(benzo[]thio-phen-2-yl)ethen-yl]-5-fluoro-phen-yl}--(but-2-yn-1-yl)benzene-sulfonamide. | LitMetric

In the title compounds, CHFNOS () and CHFNOS (), the benzo-thio-phene rings are essentially planar with maximum deviations of 0.009 (1) and 0.001 (1) Å for the carbon and sulfur atom in compounds and , respectively. In , the thio-phene ring system is almost orthogonal to the phenyl ring attached to the sulfonyl group, with a dihedral angle of 77.7 (1)°. In compound , the mol-ecular structure is stabilized by weak C-H⋯O intra-molecular inter-actions formed by the sulfone oxygen atoms, which generate two (5) ring motifs. In the crystal of , N-H⋯O hydrogen bonds link the mol-ecules into (8) rings, which are connected into a (10) chain C-H⋯F hydrogen bonds. Inter-molecular C-H⋯π inter-actions are also observed. In compound , the mol-ecules are linked C-H⋯O and C-H⋯F hydrogen bonding, generating infinite (11) and (13) chains running parallel to [010].

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439409PMC
http://dx.doi.org/10.1107/S2056989023006096DOI Listing

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