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http://dx.doi.org/10.1016/j.jdcr.2023.05.029 | DOI Listing |
JAAD Case Rep
August 2023
Department of Dermatology, Department of Medicine, Princess Norah Oncology Center, King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Indian J Dermatol
January 2023
From the Department of Dermatology, Venereology and Leprosy, SS Institute of Medical Sciences and Research Centre, Davanagere, Karnataka, India.
J Med Case Rep
August 2021
Endocrine unit, Department of Paediatrics, University of Nigeria, Ituku Ozalla, Enugu, Nigeria.
Background: Becker's nevus syndrome is a syndrome characterized by the presence of a Becker's nevus with ipsilateral breast hypoplasia or hypoplastic defects of the muscle, skin, or skeleton. The nevus usually consists of a circumscribed, unilateral, irregularly shaped hyperpigmented macule, commonly occurring around the anterior upper trunk, with/without hypertrichosis and/or acneiform lesions. This rare syndrome has not been reported in our locality to the best of our knowledge.
View Article and Find Full Text PDFAnn Dermatol Venereol
November 2010
Hôpital Saint-Louis, AP-HP, Paris, France.
Background: Cetuximab is a chimeric monoclonal antibody selective for epidermal growth factor receptor (EGFR). It is increasingly used in epithelial cancer, often in combination with radiotherapy or chemotherapeutic agents, since it induces a broad range of cellular responses that enhance tumour sensitivity to these therapies. However, it can cause numerous adverse effects, the most common being acneiform eruption on the face and trunk, which is generally bilateral and symmetric.
View Article and Find Full Text PDFIt is the purpose of this review to extend our understanding of the fibroblast growth factor (FGF) receptor-2b-signaling network in the pathogenesis of acne. A new concept of the role of FGFR2b-signaling in dermal-epithelial interaction for skin appendage formation, pilosebaceous follicle homeostasis, comedogenesis, sebaceous gland proliferation and lipogenesis is presented. The FGFR2-gain-of-function mutations in Apert syndrome and unilateral acneiform nevus are most helpful model diseases pointing the way to androgen-dependent dermalepithelial FGFR2-signaling in acne.
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