AI Article Synopsis
- PFCs are biocompatible and non-toxic compounds used in medical imaging and therapeutics, showing promise as oxygen carriers for tumor treatment.
- They are utilized in various forms, such as nanoemulsions and nanoparticles, to improve diagnostic imaging and to help prevent thrombus formation and deliver medication through ultrasound.
- The review focuses on recent advances in PFC applications for theranostic purposes and evaluates their advantages and disadvantages in clinical settings.
Article Abstract
Perfluorocarbon (PFC) are biocompatible compounds, chemically and biologically inert, and lacks toxicity as oxygen carriers. PFCs nanoemulsions and nanoparticles (NPs) are highly used in diagnostic imaging and enable novel imaging technology in clinical imaging modalities to notice and image pathological and physiological alterations. Therapeutics with PFCs such as the innovative approach to preventing thrombus formation, PFC nanodroplets utilized in ultrasonic medication delivery in arthritis, or PFC-based NPs such as Perfluortributylamine (PFTBA), Pentafluorophenyl (PFP), Perfluorohexan (PFH), Perfluorooctyl bromide (PFOB), and others, recently become renowned for oxygenating tumors and enhancing the effects of anticancer treatments as oxygen carriers for tumor hypoxia. In this review, we will discuss the recent advancements that have been made in PFC's applications in theranostic (therapeutics and diagnostics) as well as assess the benefits and drawbacks of these applications.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436007 | PMC |
| http://dx.doi.org/10.3389/fbioe.2023.1115254 | DOI Listing |
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