Rare diphenylheptanoid-phenylheptanoid hybrids with α-glucosidase inhibitory effects from the pollen of .

Two rarely occurring diphenylheptanoid-phenylheptanoid hybrid dimers ( and ) and one new oxygenated fatty acid (), as well as two known fatty acid analogues ( and ), were isolated from the 70% EtOH extract of the pollen of . Their planar structures were established by interpretation of MS and NMR spectroscopic data, and the absolute configurations of and were determined by Mosher's method and quantum chemical TD-DFT calculations of ECD spectra. An anti-diabetic evaluation of these isolates revealed that compounds and exhibited promising inhibitory activity against α-glucosidase with IC values of 11.85 ± 0.69 and 17.06 ± 3.08 μM, respectively. It is the first report on both diphenylheptanoid constituents and α-glucosidase inhibitors from the title plant, which represents a significant phytochemical progress of this herbal species and may serve as a reference for its future medicinal applications.