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A new endoscopic tumor grading for rectal neuroendocrine tumors: Correlation of vascular pattern with histopathology.
Dig Liver Dis
December 2024
Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China; Shandong Provincial Clinical Research Center for digestive disease, Shandong, China; Laboratory of Translational Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China; Robot engineering laboratory for precise diagnosis and therapy of GI tumor, Qilu Hospital of Shandong University, Jinan, Shandong, China. Electronic address:
Introduction: The clinical utility of applying endoscopic vascular patterns in rectal neuroendocrine tumor (NET) remains unknown. The aims of this study were to develop a system for utilizing vascular patterns for tumor grade and submucosal invasion depth.
Methods: We retrospectively included patients diagnosed as well-differentiated rectal NET between March 2015 and February 2024.
Ga-DOTATOC Uptake by Stellate Ganglia, Mimicking a Right Cervical Metastasis of Neuroendocrine Tumors: A Case Report.
J Clin Med
December 2024
Nuclear Medicine, Theageneio Cancer Center, 546 39 Thessaloniki, Greece.
Ga-DOTATOC PET/CT is a functional imaging modality that has revolutionized the evaluation of well-differentiated neuroendocrine tumors (NETs) by targeting somatostatin receptors. This technique has largely replaced conventional gamma camera imaging with 111In-labeled octreotide due to its superior sensitivity and resolution. While the physiologic distribution, normal variations, and common pitfalls associated with Ga-DOTATOC imaging are well documented, rare but clinically significant pitfalls can still occur.
View Article and Find Full Text PDFTemozolomide and capecitabine regimen as first-line treatment in advanced gastroenteropancreatic neuroendocrine tumors at a Latin American reference center.
World J Gastrointest Oncol
December 2024
Department of Oncology, Instituto Nacional de Enfermedades Neoplásicas, Lima 15038, Perú.
Background: Numerous studies have indicated that the temozolomide and capecitabine regimen (TEMCAP) exhibits a certain level of efficacy in treating advanced, well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NET). However, published data from Peru are limited. We hypothesize that this regimen could be a viable therapeutic option for advanced GEP-NET in the Peruvian population.
View Article and Find Full Text PDFMixed pancreatic ductal adenocarcinoma and well-differentiated neuroendocrine tumor: A case report.
World J Gastrointest Oncol
December 2024
Department of Pathology, Cooper University Hospital, Camden, NJ 08103, United States.
Background: Pancreatic mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are rare malignancies affecting the pancreas. The World Health Organization defines MiNENs as neoplasms composed of morphologically recognizable neuroendocrine and non-neuroendocrine components, each constituting 30% or more of the tumor volume. Adenocarcinoma-neuroendocrine carcinoma is the most frequent MiNEN combination.
View Article and Find Full Text PDFNeuroendocrine neoplasms of the breast: a multicenter retrospective Italian study.
Minerva Endocrinol (Torino)
December 2024
Unit of Anatomic Pathology, Department of Woman and Child Health and Public Health, IRCCS A. Gemelli University Polyclinic Foundation, Rome, Italy.
Background: The aim of our retrospective study was to describe the immunophenotypic characteristics of neuroendocrine breast neoplasm (BNEN), a peculiar and rare type of breast carcinoma.
Methods: Pathological data from 51 patients affected by BNEN were retrospectively evaluated, and 44 patients were considered eligible (7 patients with incomplete data were excluded). The patients were followed in six different Italian hospitals between 2009 and 2019.
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