Feel so bac: is Fusobacterium the suspect causing endometriosis?
Trends Mol Med
Institute of Basic Medical Sciences, National Cheng Kung University Hospital, 1 University Road, Tainan 70101, Taiwan; Department of Physiology, College of Medicine, National Cheng Kung University, National Cheng Kung University Hospital, 1 University Road, Tainan 70101, Taiwan. Electronic address:
Published: October 2023
Recent work by Muraoka and colleagues reports that the Gram-negative anaerobic bacterium Fusobacterium nucleatum is detected in the uterus of 64% of women with endometriosis. Fusobacterium infection causes macrophage infiltration, transforming growth factor-β production, and transgelin upregulation in human and mouse endometria as well as endometriotic lesion development in a mouse model of endometriosis.
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| http://dx.doi.org/10.1016/j.molmed.2023.08.003 | DOI Listing |
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