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Acute kidney injury in critical care: complications of hemophagocytic lymphohistiocytosis.
Front Immunol
July 2024
Department of Critical Care Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Article Synopsis
- Hemophagocytic lymphohistiocytosis (HLH) is a serious immune problem that causes extreme inflammation and can damage organs, including the kidneys.
- It can be either primary (caused by genetic issues) or secondary (linked to infections or diseases) and can be hard to tell apart from severe infections like sepsis.
- Signs of HLH include high fever, liver and spleen enlargement, and blood issues, but special tests can help figure it out, especially since kidney problems often happen with HLH too.
Macrophage activation syndrome in juvenile dermatomyositis: a case report and a comprehensive review of the literature.
Pediatr Rheumatol Online J
September 2023
Department of Rheumatology, Key Laboratory of Myositis, China-Japan Friendship Hospital, Beijing, China.
Background: Macrophage activation syndrome (MAS) is a severe and life-threatening syndrome associated with autoimmune diseases. The coexistence of MAS and juvenile dermatomyositis (JDM) is not well reported. This report describes a case of JDM with MAS and summarizes the clinical characteristics and prognosis of MAS in patients with JDM.
View Article and Find Full Text PDFEpstein Barr Virus-Related Acute Liver Failure and Hemophagocytosis in an Immunocompetent Individual: An Autopsy Report.
Int J Surg Pathol
June 2024
Department of Virology, PGIMER, Chandigarh, India.
Epstein-Barr virus (EBV) is a nonhepatotropic virus. It causes mild self-limiting illness characterized by fever, oral ulcer, diarrhea, lymphadenopathy, and hepatosplenomegaly. Rarely it causes acute liver failure (ALF).
View Article and Find Full Text PDFInterstitial hemophagocytosis in hemophagocytic lymphohistiocytosis.
Kidney Int
September 2023
Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
[Clinical analysis of 5 cases of dermatomyositis complicated with macrophage activation syndrome].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2022
Department of Rheumatology and Immunology, Peking University People' s Hospital, Beijing 100044, China.
To investigate the clinical and immunological features of dermatomyositis (DM) complicated with macrophage activation syndrome (MAS). The demographic and clinical characteristics of five patients diagnosed with DM complicated with MAS hospitalized in the Department of Rheumatology and Immunology, Peking University People ' s Hospital from 2011 to 2021 were collected. The results of clinical manifestations, laboratory tests, immunological features, treatments and prognosis were analyzed and summarized.
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