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PrÉcis: A hybrid deep-learning model combines NFL reflectance and other OCT parameters to improve glaucoma diagnosis.
Objective: To investigate if a deep learning model could be used combine nerve fiber layer (NFL) reflectance and other OCT parameters for glaucoma diagnosis.
Patients And Methods: This is a prospective observational study where of 106 normal subjects and 164 perimetric glaucoma (PG) patients.
Ab-Externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma: Two-Year Results from a Randomized, Multicenter Study.
Ophthalmology
March 2024
NIHR Moorfields Biomedical Research Centre, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, England; UCL Institute of Ophthalmology, London, England.
Purpose: To compare the effectiveness and safety of the MicroShunt (Santen Inc) versus trabeculectomy in patients with primary open-angle glaucoma (POAG).
Design: Prospective, randomized, multicenter trial conducted in the United States and Europe.
Participants: Adult patients (aged 40-85 years) with mild to severe POAG inadequately controlled on maximum tolerated medical therapy and intraocular pressure (IOP) ≥ 15 mmHg and ≤ 40 mmHg.
Outcomes of microPulse transscleral laser therapy in eyes with prior glaucoma aqueous tube shunt.
Graefes Arch Clin Exp Ophthalmol
October 2023
Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, 625 S Fair Oaks Ave Suite 285, Pasadena, CA, 91105, USA.
Purpose: To evaluate the outcomes of micropulse transscleral laser therapy (MP-TLT) in patients with uncontrolled glaucoma and prior glaucoma aqueous tube shunt.
Methods: In this single‑center, retrospective, interventional case series, eyes that underwent MP-TLT and had prior glaucoma aqueous tube shunt surgeries were included. The Cyclo Glaucoma Laser System (IRIDEX Corporation, Mountain View, CA, USA) with the MicroPulse P3 probe (version 1) was used.
Intraocular Pressure and Medication Changes Associated with Xen Gel Stent: A Systematic Review of the Literature.
Clin Ophthalmol
January 2023
Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT, USA.
The Xen gel stent (Allergan Inc, an AbbVie company; Dublin, Ireland) was conceived as an option for patients requiring modest IOP reduction but for whom trabeculectomy was not yet indicated. As with any glaucoma surgery, establishing criteria for patient selection and identifying factors that contribute to a high likelihood of success are important. To help guide clinical decision-making, a systematic review of published studies on the gel stent was performed, with the goal of understanding postoperative outcomes based on clinical and patient factors.
View Article and Find Full Text PDFEvidence-Based Consensus Guidelines Series for MicroPulse Transscleral Laser Therapy - Surgical Technique, Post-Operative Care, Expected Outcomes and Retreatment/Enhancements.
Clin Ophthalmol
January 2023
Ophthalmic Consultants of Connecticut, Fairfield, CT, USA.
Purpose: To provide expert consensus and evidence-based current guidelines on treatment technique, postoperative care, expected outcomes and retreatment for MicroPulse Transscleral Laser Treatment (TLT).
Methods: A comprehensive search of PubMed led to the identification and analysis of 61 studies on MicroPulse TLT. To provide guidance in areas where there was not enough available literature, a three-round Delphi method was conducted involving 10 international experts in MicroPulse TLT.
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