A cutaneous horn is a rare, hyperkeratotic, projecting lesion that can be mostly found in sun-exposed areas of the skin. The base of the lesions can reveal an underlying malignancy. They can also be associated with several benign or pre-malignant dermatologic conditions. A biopsy of the base of the lesion and histopathological analysis are needed to confirm the diagnosis. Management depends on the underlying disease; however, surgical excision is the preferred treatment method.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427885 | PMC |
| http://dx.doi.org/10.7759/cureus.41987 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin.
Cancer Cell
December 2024
Center for Cancer Immunology, Krantz Family Center for Cancer Research, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:
Immunosuppression commonly disrupts the homeostasis of mutated normal skin, leading to widespread skin dysplasia and field cancerization. However, the immune system's role in maintaining the normal state of mutated tissues remains uncertain. Herein, we demonstrate that T cell immunity to cutaneotropic papillomaviruses promotes the homeostasis of ultraviolet radiation-damaged skin.
View Article and Find Full Text PDFArticle Synopsis
- Cutaneous melanoma (CM) and non-melanoma skin cancer (NMSC) rates are increasing in postmenopausal women, but the impact of vitamin A on their risk remains unclear.
- A study of 52,877 White women found no link between total vitamin A intake and melanoma risk; however, higher dietary vitamin A and beta-cryptoxanthin were correlated with an increased risk of NMSC.
- The findings suggest that while vitamin A does not lower CM or NMSC risk, higher dietary intakes may actually increase NMSC risk in this demographic.
A Case of Basal Cell Carcinoma Exacerbated with Akatsuki Disease.
Dermatopathology (Basel)
November 2024
Department of Dermatology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku 783-8505, Kochi, Japan.
Akatsuki disease (also known as pomade crust) is characterized by skin lesions resulting from inadequate skin hygiene. It is sometimes influenced by underlying psychological factors. Akatsuki disease sometimes mimics cutaneous horn or skin cancer.
View Article and Find Full Text PDFClinical and histopathological features of advanced cutaneous squamous cell carcinoma with varying responses to cemiplimab.
J Dtsch Dermatol Ges
November 2024
Department of Dermatology, Venereology und Allergology, University Medical Center Leipzig, Leipzig, Germany.
Background: Most patients with unresectable locally advanced cutaneous squamous cell carcinoma (cSCC) benefit from cemiplimab, but some do not respond. Our study aims to identify clinical and histopathological features predicting response to cemiplimab.
Patients And Methods: We analyzed 15 patients treated with cemiplimab, assessing clinical, demographic, histopathological, and immunohistochemical characteristics and correlating them with treatment response.
Nodular Melanoma Presenting with Cutaneous Horn and Displaying Rhabdoid Features: An Unusual Presentation.
J Coll Physicians Surg Pak
November 2024
Department of Pathology, Faculty of Medicine, Duzce University, Duzce, Turkiye.
Article Synopsis
- Null can signify the absence of a value or a concept in programming and mathematics.
- It often indicates that a variable has no assigned data or an object is uninitialized.
- In philosophical terms, null might refer to the idea of non-existence or emptiness.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!