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Melioidosis - An under-recognized dreaded disease in Southeast Asia.
Turk J Emerg Med
January 2025
Department of Emergency Medicine and Trauma, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Melioidosis is a disease endemic to India but often goes unrecognized, leading to considerable illness and death. We present the case of a 31-year-old man who had a fever of unknown origin, abnormal renal and liver function tests, and negative tests for dengue, typhoid, leptospirosis, and scrub typhus. Imaging revealed multiple splenic infarcts.
View Article and Find Full Text PDFDeveloping a clinical prediction model to modify empirical antibiotics for non-typhoidal Salmonella bloodstream infection in children under-five in the Democratic Republic of Congo.
BMC Infect Dis
January 2025
Department of Development and Regeneration, KU Leuven, Louvain, Belgium.
Background: Non-typhoidal Salmonella (NTS) frequently cause bloodstream infection in children under-five in sub-Saharan Africa, particularly in malaria-endemic areas. Due to increasing drug resistance, NTS are often not covered by standard-of-care empirical antibiotics for severe febrile illness. We developed a clinical prediction model to orient the choice of empirical antibiotics (standard-of-care versus alternative antibiotics) for children admitted to hospital in settings with high proportions of drug-resistant NTS.
View Article and Find Full Text PDFA systematic review of recent outbreaks and the efficacy and safety of drugs approved for the treatment of infections.
IJID Reg
March 2025
Department of Pharmacy Practice, School of Pharmacy, IMU University, Kuala Lumpur, Malaysia.
A systematic review was conducted to critically analyze the outbreaks, efficacy, and safety of drugs used to treat various infections. Four drugs-azithromycin, ceftriaxone, ciprofloxacin, and amoxicillin-are commonly used to treat infections, and all four drugs were included in this review. This review found that, of these, azithromycin and ceftriaxone were more effective in treating infections based on the patient's length of stay in the hospital and the rate at which the fever was resolved.
View Article and Find Full Text PDFRare but dangerous cause of non-purulent myopericarditis: a non-typhoidal infection.
BMJ Case Rep
January 2025
Cardiology, Montefiore Hospital and Medical Center, Bronx, New York, USA.
We present a case of a young man in his early 20s who presented to the hospital with acute onset of central chest pain, preceded by epigastric fullness and diarrhoea 5 days after consuming a meal containing chicken products. Following an extensive evaluation, he was diagnosed with -associated myopericarditis. This case aims to raise awareness within the medical community about the cardiac effects of infection.
View Article and Find Full Text PDFTyphoid Fever as a Cause of Liver Failure in the United States: A Case Report.
Case Rep Gastrointest Med
January 2025
Department of Infectious Diseases, Maimonides Medical Center, Brooklyn, New York 11219, USA.
Typhoid fever is a multisystemic illness caused by and , transmitted fecal orally through contaminated water and food. It is a rare diagnosis in the US, with most cases reported in returning travelers. Hepatitis and cholestasis are rare sequelae of infection.
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