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Paclitaxel-induced dorsal hand-foot syndrome. | LitMetric

Paclitaxel-induced dorsal hand-foot syndrome.

Dermatol Online J

Section of Dermatology, Department of Internal Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA.

Published: June 2023

AI Article Synopsis

  • Hand-foot syndrome (HFS) is an adverse effect of chemotherapy that causes discomfort and redness primarily on the palms and soles of the feet.
  • Paclitaxel, though an uncommon cause of HFS, can manifest in an unusual way on the dorsal (top) surfaces of the hands and feet.
  • A case is presented involving a 66-year-old man with metastatic angiosarcoma experiencing HFS on his dorsal hands, highlighting the importance of early detection and management to maintain chemotherapy and enhance the patient's quality of life.

Article Abstract

Hand-foot syndrome (HFS), also known as palmoplantar erythrodysesthesia or acral erythema, is a known adverse effect of chemotherapeutic agents that most commonly presents as palmoplantar dysesthesia and erythematous plaques localized to the palms and soles. Paclitaxel is an uncommon cause of HFS and is notable for its unique presentation on the dorsal hands and feet. We present an unusual case of paclitaxel-induced HFS localized to the dorsal hands of a 66-year-old man with metastatic angiosarcoma. Early identification and management of HFS is critical to allow for continuation of chemotherapy while improving patient quality of life.

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Source
http://dx.doi.org/10.5070/D329361434DOI Listing

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