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| http://dx.doi.org/10.1523/JNEUROSCI.0865-23.2023 | DOI Listing |
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The cognitive critical brain: Modulation of criticality in perception-related cortical regions.
Neuroimage
January 2025
Department of Psychology & Tsinghua Laboratory of Brain and Intelligence, Tsinghua University, Beijing, China. Electronic address:
The constantly evolving world necessitates a brain that can swiftly adapt and respond to rapid changes. The brain, conceptualized as a system performing cognitive functions through collective neural activity, has been shown to maintain a resting state characterized by near-critical neural dynamics, positioning it to effectively respond to external stimuli. However, how near-criticality is dynamically modulated during task performance remains insufficiently understood.
View Article and Find Full Text PDFBanked Primary Progenitor Cells for Allogeneic Intervertebral Disc (IVD) Therapy: Preclinical Qualification and Functional Optimization within a Cell Spheroid Formulation Process.
Pharmaceutics
September 2024
Development Department, LAM Biotechnologies SA, CH-1066 Epalinges, Switzerland.
Biological products are emerging as therapeutic management options for intervertebral disc (IVD) degenerative affections and lower back pain. Autologous and allogeneic cell therapy protocols have been clinically implemented for IVD repair. Therein, several manufacturing process design considerations were shown to significantly influence clinical outcomes.
View Article and Find Full Text PDFPressure-Tuned Quantum Criticality in the Locally Noncentrosymmetric Superconductor CeRh_{2}As_{2}.
Phys Rev Lett
September 2024
Institute for Solid State and Materials Physics, TU Dresden University of Technology, 01062 Dresden, Germany.
The unconventional superconductor CeRh_{2}As_{2} (critical temperature T_{c}≈0.4 K) displays an exceptionally rare magnetic-field-induced transition between two distinct superconducting (SC) phases, proposed to be states of even and odd parity of the SC order parameter, which are enabled by a locally noncentrosymmetric structure. The superconductivity is preceded by a phase transition of unknown origin at T_{0}=0.
View Article and Find Full Text PDFHair cells in the cochlea must tune resonant modes to the edge of instability without destabilizing collective modes.
bioRxiv
July 2024
Department of Physics, Yale University, New Haven, CT 06520 and Quantitative Biology Institute, Yale University, New Haven, CT 06520.
Sound produces surface waves along the cochlea's basilar membrane. To achieve the ear's astonishing frequency resolution and sensitivity to faint sounds, dissipation in the cochlea must be canceled via active processes in hair cells, effectively bringing the cochlea to the edge of instability. But how can the cochlea be globally tuned to the edge of instability with only local feedback? To address this question, we use a discretized version of a standard model of basilar membrane dynamics, but with an explicit contribution from active processes in hair cells.
View Article and Find Full Text PDFQuantum Criticality with Emergent Symmetry in the Extended Shastry-Sutherland Model.
Phys Rev Lett
July 2024
Department of Physics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
Motivated by the novel phenomena observed in the layered material SrCu_{2}(BO_{3})_{2}, the Shastry-Sutherland model (SSM) has been extensively studied as the minimal model for SrCu_{2}(BO_{3})_{2}. However, the nature of its quantum phase transition from the plaquette valence-bond solid to antiferromagnetic phase is under fierce debate, posing a challenge to understand the underlying quantum criticality. Via the state-of-the-art tensor network simulations, we study the ground state of the SSM on large-scale size up to 20×20 sites.
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