Nigeria's under five-mortality was 132 per 1000 in 2018. The statistic makes Nigeria the country with the third-highest under-five mortality globally. It implies that the government may not achieve the Sustainable Development Goal (SDG) of 25 per 1000 births by 2030. This situation is of grave concern to policymakers and other stakeholders interested in the country's development. This study provides unique community micro-level information on child mortality determinants in rural communities where the country's health system is weakest. The study used a sample of 1350 pregnant women aged 20-44 who attended antenatal care in22 health facilities in selected rural communities of Ogun State, South-west Nigeria. The multicollinearity diagnostics tests conducted between the dependent variable and predictors showed no abnormality in the values of the variance inflation factor, eigenvalues, and condition indexes. Logistics regression results showed that the socio-demographic characteristics such as the respondent's age, educational level, number of living children, and husband's education directly affected child mortality. In contrast, the husband has another wife had an indirect effect on child mortality. Environmental factors that directly impacted child mortality included the type of household toilet facility, source of water supply, and household waste disposal practices. These findings indicate that policies and programs to reduce child mortality in rural Nigeria must address socio-demographic and context-specific factors, especially at the community level.
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http://dx.doi.org/10.29063/ajrh2021/v25i5s.15 | DOI Listing |
Public Health Nutr
January 2025
Faculty of Economics and Management, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Objective: To investigate the relationship between maternal age and nutritional status, and test associations between maternal nutritional status and child mortality with a focus on maternal obesity.
Design: Secondary analysis of data from nationally representative cross-sectional sample of women of reproductive ages (15-49 years) and their children under five years. The outcome variable for maternal nutritional status was Body Mass Index (BMI), classified into underweight (BMI < 18.
Matern Child Nutr
January 2025
School of Health Science, Western Sydney University, Campbelltown, NSW, Australia.
Early initiation of breastfeeding (EIBF) and exclusive breastfeeding (EBF) are highly effective forms of preventive medicine in many low- and middle-income countries, including Anglophone and Francophone West African countries. Despite the proven benefits of EIBF and EBF in reducing mortality and morbidity, there is limited systematic evidence from West African countries. Hence, the aim of this systematic review and meta-analysis was to estimate the pooled prevalence of EIBF and EBF in Anglophone and Francophone West African countries.
View Article and Find Full Text PDFEClinicalMedicine
December 2024
University of North Carolina Project-China, Guangzhou, China.
Background: Adolescents (10-19 years old) have poor outcomes across the prevention-to-treatment HIV care continuum, leading to significant mortality and morbidity. We conducted a systematic review and meta-analysis of interventions that documented HIV outcomes among adolescents in HIV high-burden countries.
Methods: We searched PubMed, EMBASE, Scopus, and the Cochrane Library for studies published between January 2015 and September 2024, assessing at least one HIV outcome along the prevention-to-care cascade, including PrEP uptake, HIV testing, awareness of HIV infections, ARV adherence, retention, and virological suppression.
Front Pediatr
December 2024
Department of Pediatrics, Division of Neonatology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Zinc (Zn) is one of the most prevalent and essential micronutrients, found in 10% of all human proteins and involved in numerous cellular enzymatic pathways. Zn is important in the neonatal brain, due to its involvement in neurotransmission, synaptic plasticity, and neural signaling. It acts as a neuronal modulator and is highly concentrated in certain brain regions, such as the hippocampus, and the retina.
View Article and Find Full Text PDFClin Transl Med
January 2025
Frazer Institute, Faculty of Medicine, The University of Queensland, Woolloongabba, Queensland, Australia.
Background: Paediatric sarcomas, including rhabdomyosarcoma, Ewing sarcoma and osteosarcoma, represent a group of malignancies that significantly contribute to cancer-related morbidity and mortality in children and young adults. These cancers share common challenges, including high rates of metastasis, recurrence or treatment resistance, leading to a 5-year survival rate of approximately 20% for patients with advanced disease stages. Despite the critical need, therapeutic advancements have been limited over the past three decades.
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