The United States government, under President Donald Trump, retreated from its traditional role as an exemplar of democracy, defender of press freedom and the rule of law but embraced conspiracy theories, virulent anti-Semites, and authoritarian regimes worldwide. Today, democracy is in crisis and is under assault and in retreat globally. The 2022 United States midterm election has come and is now history with many unexpected outcomes. The three impactful issues during the campaign that produced many upsets were abortion rights, election denialism, and threats to democracy. This editorial examines the history of abortion rights in the United States, the impacts of the Dobbs vs. Jackson ruling on the 2022 midterm election, the threats of election deniers to global democracy, the global status of reproductive health rights, and the lessons of abortion ban for burgeoning democracies worldwide.
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http://dx.doi.org/10.29063/ajrh2023/v27i2.1 | DOI Listing |
Elife
December 2024
Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
Previously, we reported that α-synuclein (α-syn) clusters synaptic vesicles (SV) Diao et al., 2013, and neutral phospholipid lysophosphatidylcholine (LPC) can mediate this clustering Lai et al., 2023.
View Article and Find Full Text PDFJ Med Internet Res
December 2024
Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Background: Large language models (LLMs) are increasingly integrated into medical education, with transformative potential for learning and assessment. However, their performance across diverse medical exams globally has remained underexplored.
Objective: This study aims to introduce MedExamLLM, a comprehensive platform designed to systematically evaluate the performance of LLMs on medical exams worldwide.
J Am Chem Soc
December 2024
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, United States.
We present a six-step cascade that converts 1,3-distyrylbenzenes (-stilbenes) into nonsymmetric pyrenes in 40-60% yields. This sequence merges photochemical steps, ,-alkene isomerization, a 6π photochemical electrocyclization (Mallory photocyclization); the new bay region cyclization, with two radical iodine-mediated aromatization steps; and an optional aryl migration. This work illustrates how the inherent challenges of engineering excited state reactivity can be addressed by logical design.
View Article and Find Full Text PDFJMIR Infodemiology
December 2024
Department of Computer Science, University of Saskatchewan, Saskatoon, SK, Canada.
Background: Understanding advocacy strategies is essential to improving dementia awareness, reducing stigma, supporting cognitive health promotion, and influencing policy to support people living with dementia. However, there is a dearth of evidence-based research on advocacy strategies used to support dementia awareness.
Objective: This study aimed to use posts from X (formerly known as Twitter) to understand dementia advocacy strategies during World Alzheimer's Awareness Month in September 2022.
Elife
December 2024
Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Chemotherapy is widely used to treat lung adenocarcinoma (LUAD) patients comprehensively. Considering the limitations of chemotherapy due to drug resistance and other issues, it is crucial to explore the impact of chemotherapy and immunotherapy on these aspects. In this study, tumor samples from nine LUAD patients, of which four only received surgery and five received neoadjuvant chemotherapy, were subjected to scRNA-seq analysis.
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