AI Article Synopsis

  • Phytophotodermatitis is a skin condition caused by exposure to certain plants with phototoxic chemicals, followed by sunlight, leading to skin irritation and damage.
  • A case study of a 55-year-old man showed he developed painful skin lesions after handling figs in the sun, which were diagnosed as phytophotodermatitis through testing.
  • Diagnosis involves a thorough patient history and testing to identify plant triggers, and while the condition is usually self-limiting, avoiding the specific plants is recommended for prevention.

Article Abstract

Phytophotodermatitis, a condition that results from sequential skin exposure to phototoxic chemicals contained within plants, followed by exposure to solar ultraviolet radiation, has been described with several plants and plant-based foods, namely members of the family, which include L. This tree's branches, leaves, and fruit skin exude a milky sap or latex containing proteolytic enzymes and furocoumarins known to be photoirritants, easily absorbed upon skin contact. Oxygen-dependent and independent toxic reactions subsequent to sun exposure promote cell membrane damage and oedema, consequently leading to cell death. The diagnosis is confirmed with a detailed anamnesis, and photopatch testing is often useful to rule out a differential diagnosis. It is typically a self-limited condition, with few cases requiring treatment with topical or systemic corticosteroids. We report on a 55-year-old male patient who, following picking figs and pruning a fig tree while exposed to sunlight, developed erythematous and pruritic maculopapular lesions that progressed to blisters with residual hyperpigmentation. The diagnosis was further corroborated through photopatch testing, and the patient was recommended to avoid this recreational activity without symptoms' relapse. This case highlights the importance of considering phytophotodermatitis as a differential diagnosis when evaluating cases of dermatitis on exposed body surfaces and the importance of an exhaustive anamnesis. Identification of specific plant triggers and the performance of photopatch tests are essential to help confirm the diagnosis and guide avoidance recommendations.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423627PMC
http://dx.doi.org/10.7759/cureus.41888DOI Listing

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