Effect of serum apelin and elabela levels in pregnancies complicated with preeclampsia in association to BMI, CRP and parity.

Hypertensive disorders of pregnancy are a serious and life-threatening condition often complicating the pregnancy leading to preeclampsia, eclampsia, maternal and neonatal mortality and morbidity. Preeclampsia is myriad of diseases starting from improper remodeling of spiral arteries, poor placentation leading to fatal consequences of intrauterine fetal and maternal death due to uncontrolled blood pressure. Thirty-three preeclamptic women in Group 1 and thirty-three healthy pregnant in group 2 has been taken in this research. Statistical analysis and evaluation were performed by utilizing SPSS version 23.0. Result of our research show significant decrease in serum apelin and elabela and association of these hormones with parity, body mass index (BMI), C-reactive protein (CRP) , systolic and diastolic blood pressure in preeclamptic women as compared to healthy pregnant while no significant association with age.