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Recognizing red flags for alternative diagnoses in pediatric chorea beyond Sydenham's.
Brain Dev
November 2024
General Practice, HOMI Fundación Hospital Pediátrico la Misericordia, Bogotá, Colombia.
Article Synopsis
- Chorea is a movement disorder in children that requires careful diagnosis to identify treatable underlying conditions, which can enhance their quality of life.
- A study conducted on 81 pediatric patients in Bogotá identified rheumatic fever as the most common cause of chorea, followed by vascular issues and lupus, with older children more likely to have rheumatic fever.
- The research highlighted key indicators for differentiating causes, such as age and accompanying neurological symptoms, and found a significant relationship between age and psychiatric symptoms, showing these symptoms are common in children with movement disorders.
Treatable Sydenham Chorea in a 76-Year-Old Woman.
Neurology
November 2023
From the Departments of Neurology (A.K., A.S.), Neuroradiology (C.S.), and Nuclear Medicine (F.C.R.), Zentralklinik Bad Berka; Department of Neurology (A.K.), University Hospital Jena, Germany.
Autoimmune and Paraneoplastic Chorea: A Review of the Literature.
Front Neurol
March 2022
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Autoimmune chorea syndromes represent a vast array of paraneoplastic, parainfectious and idiopathic disorders. It is increasingly apparent that familiarity with these disorders is critically important, as they may be treatable or may be part of a syndrome requiring further work-up and monitoring. These disorders are mediated by an aberrant immunologic attack with resultant neuronal dysfunction, manifesting as chorea.
View Article and Find Full Text PDFAcute chorea: case series from the emergency room of a Brazilian tertiary-level center.
Arq Neuropsiquiatr
March 2021
Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Neurologia, São Paulo SP, Brazil.
Background: Chorea is a movement disorder characterized by random, brief and migratory involuntary muscle contractions. It is defined as acute when present within hours to days. Three main causes for this scenario have emerged as most likely: vascular, toxic-metabolic and inflammatory.
View Article and Find Full Text PDFAntibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders.
Brain
November 2012
Neuroimmunology group, Institute for Neuroscience and Muscle Research, The Kids Research Institute at the Children’s Hospital at Westmead, University of Sydney, Westmead NSW 2145, Australia.
Recent reports of autoantibodies that bind to neuronal surface receptors or synaptic proteins have defined treatable forms of autoimmune encephalitis. Despite these developments, many cases of encephalitis remain unexplained. We have previously described a basal ganglia encephalitis with dominant movement and psychiatric disease, and proposed an autoimmune aetiology.
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