AI Article Synopsis
- Hemophagocytic lymphohistiocytosis (HLH) is a severe inflammatory syndrome that can be genetic or acquired, and it may lead to acute liver failure.
- A case report highlights the occurrence of acute liver failure linked to HLH following a COVID-19 vaccination, alongside a review of relevant literature on the topic.
- Due to the high mortality associated with HLH and the impracticality of liver transplantation, early detection and appropriate conservative treatment are crucial for improving patient outcomes.
Article Abstract
Hemophagocytic lymphohistiocytosis (HLH) is a congenital or acquired hyperinflammatory syndrome, in some cases accompanied by acute liver failure. We present a case report of acute liver failure associated with HLH after COVID-19 vaccination and bring a literature review of the connection between HLH and COVID-19 vaccination. HLH has significant mortality rate, and liver transplantation is not a therapeutic option. Therefore, early recognition and timely conservative treatment are corner stones in reducing HLH-related morbidity and mortality.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416787 | PMC |
| http://dx.doi.org/10.2147/IMCRJ.S417347 | DOI Listing |
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