Case report: Villaret's syndrome caused by middle ear adenocarcinoma in a cat.

Front Vet Sci

Department of Bio-animal Care, Jangan University, Hwaseong, Gyeonggi-do, Republic of Korea.

Published: July 2023

AI Article Synopsis

  • A 7-year-old male cat had some serious health problems, including trouble swallowing, coughing, and changes in his eye and voice.
  • Doctors used a special medicine that quickly helped some of his symptoms, which indicated that the issue was with a specific part of his nervous system.
  • After tests and surgery, they found out the cat had a type of cancer called middle ear adenocarcinoma, leading to problems with important nerves that control his throat and face.

Article Abstract

A 7-year-old castrated male American Shorthair cat presented with left-side Horner's syndrome and voice change. The overall clinical presentation included dysphagia, intermittent coughing, unilateral miosis, and third eyelid protrusion of the left eye. A topical 1% phenylephrine was applied, and miosis and protrusion of the third eyelid disappeared within 20 min which suggested a post-ganglionic lesion. Laryngoscopy showed left-sided laryngeal paralysis. Computed tomography (CT) identified a mass lesion invading outside of the left tympanic bulla with osteolysis. Endoscopically assisted ventral bulla osteotomy was performed for tumor resection and definitive diagnosis. Middle ear adenocarcinoma was diagnosed based on histopathology. It appears that these neurological signs occurred due to adenocarcinoma in the tympanic bulla, penetrating the jugular foramen and the hypoglossal canal and damaging the cranial nerve IX (glossopharyngeal nerve), X (vagus nerve), XI (accessory nerve), and XII (hypoglossal nerve) and the sympathetic nerve. To the best of our knowledge, this is the first case report of Villaret's syndrome associated with middle ear adenocarcinoma affecting the nerves passing through the jugular foramen and hypoglossal canal in cats.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413872PMC
http://dx.doi.org/10.3389/fvets.2023.1225567DOI Listing

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