Objective: To research the mechanism of acupuncture and moxibustion in treating and preventing allergic rhinitis.
Methods: We searched PubMed; Google Scholar; Semantic Scholar; Academic Keys; Citation; Dimensions; EuroPub; Index (A & HCI); Compendex; Conference Proceedings Citation; and Science Citation Index. We reviewed the mechanism of acupuncture and moxibustion in the prevention and treatment of allergic rhinitis from the perspectives of Th1/Th2 balance regulation, IgE level reduction, lowering of inflammatory cell infiltration in the nasal mucosa, regulation of nasal neuropeptide (substance P) level, inhibition of Toll-like receptors, and NFκB protein expression.
Results: Acupuncture can play a therapeutic role in AR. Combining different aspects such as the influence on Th1 and Th2 subsets of cells, regulation of Th1/Th2 balance, reduction of IgE level, reduction of inflammatory cell infiltration in the nasal mucosa, regulation of nasal neuropeptide (substance P) level, inhibition of Toll-like receptor, and NFκB protein expression, the mechanism of action of acupuncture for AR can be elucidated more comprehensively.
Conclusion: Acupuncture and moxibustion can be used to treat allergic rhinitis in several ways.
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