To assess the prevalence and pathological role of hepatitis D virus (HDV) infection in western Canada, we tested a total of 310 sera from the province of Alberta, Yukon and Northwest Territories for antibody to HD (anti-HDV) by commercial solid phase radioimmunoassay. Two hundred and forty-five sera were hepatitis B surface antigen (HBsAg) positive. These were classified on the basis of clinical and biochemical data as either acute hepatitis, chronic hepatitis or in the healthy carrier phase of infection Sixty-five HBsAg negative sera from patients with other forms of chronic liver diseases served as controls. Anti-HDV was detected in only four of the HBsAg positive sera (1.6%) and in none of the controls. The prevalence of anti-HDV was significantly higher in patients with chronic hepatitis, three of twenty-two (13.6%) than in patients with acute hepatitis (0%) (p less than 0.05) or healthy carriers (0%) (p less than 0.005). Two of the four anti-HDV positive sera were obtained from patients with a history of parenteral drug abuse. These results indicate that HDV infection is uncommon in western Canada but, when it does occur, is more likely to be associated with chronic inflammatory liver disease. Parenteral drug abuse appears to be the major risk factor for HDV infection in western Canada at this time.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Pay talk in contemporary workplaces.
Soc Forces
March 2025
National Women's Law Center, Washington, DC 20005, United States.
Drawing on a unique survey of US workers with information about their employers' policies on pay discussions and whether workers engage in such talk with their coworkers, we provide the most comprehensive investigation into pay talk in workplaces to date. Unlike existing treatments, we focus on core organizational and relational factors that influence whether workers talk about pay. We theorize pay talk as a challenge to managerial discretion, and we hypothesize that organizational attributes related to pay-setting influence workers' willingness to discuss wages and salaries with colleagues.
View Article and Find Full Text PDFSacrificial MOF-derived MnNi hydroxide for high energy storage supercapacitor electrodes via DFT-based quantum capacitance study.
Heliyon
January 2025
Materials and Process Simulation Center, California Institute of Technology, Pasadena, CA, 91125, USA.
Electrochemical energy storage plays a critical role in the transition to clean energy. With the growing demand for efficient and sustainable energy solutions, supercapacitors have gained significant attention due to their high specific capacitance, rapid charge/discharge capabilities, long lifespan, safe operation across various temperatures, and minimal maintenance needs. This study introduces a novel approach for the synthesis of high-performance supercapacitor electrodes by using MnNi-MOF-74 as a precursor.
View Article and Find Full Text PDFHistorical Depictions of the Brain: The Origins from the Non-Western World.
J Undergrad Neurosci Educ
December 2024
Department of Psychology, The University of British Columbia, Okanagan, Kelowna, BC, Canada.
Any written work concerning the history of neuroanatomy would be difficult to imagine without acknowledging the pioneering works of Santiago Ramón y Cajal and Camillo Golgi. Cajal improved upon Golgi's staining technique at the turn of the 20th century. He implemented it to deliver the world's first incredibly detailed visualizations of cellular networks of the nervous system.
View Article and Find Full Text PDFCross-cultural adaptation and evidence of validity of the interprofessional collaboration scale (IPC-BR) for Brazil.
J Interprof Care
January 2025
Graduate Program in Clinical Nursing and Health Care, State University of Ceara, Fortaleza, Brazil.
We aimed to perform cross-cultural adaptation of the Interprofessional Collaboration Scale (IPC-BR) and to evaluate evidence of its validity for the Brazilian hospital context. The research consisted of six steps: translation of the instrument into the new language, synthesis of the translated versions, back-translation, synthesis of the versions in the original language, evaluation of the syntheses by an expert committee, and pilot testing or pretesting and validation of the internal structure of the items of the instrument. The pilot testing involved 4 translators, 14 judges, and 30 healthcare professionals; the validation of the internal structure involved 686 professionals including nurses, physicians and physiotherapists.
View Article and Find Full Text PDFCharacterization of liver, adipose, and fecal microbiome in obese patients with MASLD: links with disease severity and metabolic dysfunction parameters.
Microbiome
January 2025
Toronto General Hospital, University Health Network, Toronto, Canada.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) encompasses a range of histological findings from the generally benign simple steatosis to steatohepatitis (MASH) which can progress to fibrosis and cirrhosis. Several factors, including the microbiome, may contribute to disease progression.
Results: Here, we demonstrate links between the presence and abundance of specific bacteria in the adipose and liver tissues, inflammatory genes, immune cell responses, and disease severity.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!