AI Article Synopsis
- Precision oncology focuses on tailoring cancer treatments to individual patients based on their unique molecular profiles.
- Recent advancements in genomics and functional genetics are facilitating the large-scale discovery of new molecular targets for therapy development.
- The integration of genomic data with functional genetics presents both opportunities and hurdles in identifying the next generation of effective cancer treatment targets.
Article Abstract
The success of precision oncology-which aims to match the right therapies to the right patients based on molecular status-is predicated on a robust pipeline of molecular targets against which therapies can be developed. Recent advances in genomics and functional genetics have enabled the unbiased discovery of novel molecular targets at scale. We summarize the promise and challenges in integrating genomic and functional genetic landscapes of cancer to establish the next generation of cancer targets.
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| http://dx.doi.org/10.1016/j.celrep.2023.112978 | DOI Listing |
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